Early Onset Characteristics Of Type 2 Diabetic Nephropathy With Blood Stasis And Phlegm And Blood Stasis Of Tcm By Comparative Study

Diabetic Nephropathy is one serious micrangium complication of diabetes mellitus, also known as diabetes mellitus glomerulus sclerosis, which clinical principal character is albuminuria hypertension and progressivity renal failure In Asia, Diabetic Nephropathy has been proved to be the chiefly pathogenic factor of End-stage Renal Disease, connected with cardiovascular disease risk. Diabetic Nephropathy morbidity is high, once emerge clinical albuminuria,it is hard to control patient’s condition.If controlled positively in the early days, the harm of renal can be changed over even fully recovered,so the study of DN early stage is necessary.There isn’t a name of Diabetic Nephropathy in ancient,but the characteristic of DN is similar with traditional Chinese Medicine disease,such as turbid or dropsy.Modern doctors of TCM consider the pathogenesis is that,both Qi and Yin is vain,the function of spleen and renal is abnormal, so as to nutrition leakage,blood stasis,humid turbid and sputum noxious impeded main and collateral channels,even vitality exhausted.The early stage of DN always simultaneous stasis heat humid gloomy sputum, especially stasis influence the whole course of DN.Objective:This research investigated the general information and TCM syndrome of patients who were diagnosed type2Diabetic Nephropathy early stage, analyzed relationship of different factors between blood stasis syndrome and sputum blood stasis syndrome, offering information for TCM cognition and treat.Methods:This research which collected the76cases of patients who were diagnosed type2Diabetic Nephropathy early stage, analyzed the general information and TCM syndrome by using descriptive analysis, chi-square test for enumeration data, independent samples t-test for measurement date, and analyzed relationship of different factors between blood stasis syndrome and sputum blood stasis syndrome.Results:1.In investigated cases, the male sex taked up61.8%, the female sex taked up38.2%, and the symptom which occured frequently are feeble, foamed urine, astriction, lower limb dropsy, hands and feet numb or hurt, dizziness, thirst.2.The morbidity of complication are hypertension82.19%, diabetic peripheral neuropathies41.10%, coronary heart disease31.51%, diabetic retinopathy28.77%, cerebral infarction19.18%.3.The morbidity of TCM deficiency syndrome are, both qi and yin deficiency syndrome59.42%, spleen and kidey-yang deficiency syndrome20.29%, liver and kidney-yin deficiency syndrome13.43%, qi-blood deficiency syndrome10.14%. The morbidity of TCM symptom syndrome are blood-sputum stasis syndrome50.72%, blood stasis syndrome44.93%, humid-heat syndrome11.59%, yin deficiency yang without restricted syndrome10.14%, liver constraint qi stagnation syndrome7.25%.4.The parameters of BMI, TC, LDL-C, HbA1c, Smoking history and Fatty liver medicine history in blood-sputum stasis syndrome group is higher than blood stasis syndrome group(p<0.05), and the parameters of age in blood-sputum stasis syndrome group is lower than blood stasis syndrome group(p<0.05).Conclusion:1.The patients of early type2diabetic nephropathy especially the male sex, should emphasize controlling blood sugar, hypertension, blood fat, BMI, and reasonable life-style such as no smoking and regular daily life.2.Hypertension is the highest morbidity in early type2diabetic nephropathy complications. With early type2diabetic nephropathy evolving, the morbidity of hypertension is increasing.3.In early type2diabetic nephropathy, the main TCM deficiency syndrome are qi-yin deficiency syndrome, spleen and kidey-yang deficiency syndrome, the next are liver and kidney-yin deficiency syndrome, qi-blood deficiency syndrome. The main TCM symptom syndrome are blood-sputum stasis syndrome, blood stasis syndrome, the next are humid-heat syndrome, yin deficiency yang without restricted syndrome, liver constraint qi stagnation syndrome.4.In early type2diabetic nephropathy, the badness control of BMI, TC, LDL-C, HbA1c, Fatty liver in blood-sputum stasis syndrome is more obvious than blood stasis syndrome, which is more harmful for patients’health.