The Application Of Solid Super Strong Base In Aldol Condensation

With the continuous improvement of living standards, the demand for chemicals is increasingand diversification, the chemical industries have developed rapidly. People get the wealth andconvenience in the development of the chemical industry. The pollution caused by the chemicalindustry is constantly threatening people’s health and survival. The chemical pollution is causingserious ecological disaster. For the protection of the Earth-our common home, the worldresponded with bitter reflection. The old mode of production should be eliminated and discarded.We should eliminate the pollution of the chemical industry and implement the sustainabledevelopment. With the growing awareness of social environmental protection, the research ofgreen chemistry is increasing. Chemists continue to explore new environmentally friendlycatalysts and environmentally friendly synthesis process. Therefore, green chemistry has been arapid development. The development of environmentally friendly catalysts and the synthesis ofnew technology become a hot topic in the field of chemical.Solid base and solid super base is the important one of the green catalyst. Compared with theLewis and Brφnsted catalyst, solid base have some obvious advantages. Because solid base andsolid super base have high catalytic activity, low reaction temperature, and easy to be separatedfrom the reaction, gain the products easily, no pollution to environment. Solid base and solidsuper base can be used as a new generation of environmentally friendly catalytic materials.Solid super base has become an important part of green chemistry research. Developingthe applications of solid super base, especially exploring the application of research in organicsynthesis has become a mission and research to chemists.With Interesting in new catalysts and catalytic properties, the preparation method of solidsuper base catalyst was studied. With γ-Al₂O₃sieve as the carrier, Na+was loaded in the carriersurface. A solid super base γ-Al₂O₂-O_2-2Na⁺was prepared successfully. The applications of thesolid super base catalyst in organic synthesis were studied preliminary.In the first chapter of this paper, the research of solid base catalyst and solid super basecatalyst was summarized. Such as the classification, preparation of the solid super base catalysts,methods of superficial syndrome and the application in the organic synthesis and so on. Theadvantages and disadvantages of the solid base catalyst were summarized. And the topic researchplan was proposed.In the second chapter of this paper, based on the existing research of our laboratory, the catalyst γ-Al₂O₂-O_2-2Na⁺was improved. The structure and surface properties of the obtainedmaterials were character by XRD, FT-IR, SEM, BET and the base strength of determination. Theresults showed that the catalyst had ideal structure. The base strength was H-≥37, and theγ-Al₂O₂-O_2-2Na⁺is solid super base catalyst.In the third chapter of this paper, the solid super base catalyst γ-Al₂O₂-O_2-2Na⁺was used inpreparation of α,α’-bis（benzylidene）cyclohexanones, α,α’-bis（furfuryl）cyclohexanones, α,α’-Difurf urylacetones,2,5-di（p-methoxy）cyclohexanones,2,5-di（p-methoxy）cyclopentanones. TheFT-IR and1H-NMR were characterized. The dosage of the solvent, reaction temperature,reaction time and the modification of the dosage of the super base catalyst were assessed. Theresults showed that the catalyst used in aldol reaction, the reaction temperature is low, highcatalytic efficiency, simple in the process, and environmentally friendly. The γ-Al₂O₂-O_2-2Na⁺solid super base catalyst has a broad industrial application.