Clinical Analysis Of24h Ambulatory Blood Pressure Monitoring In Patients With Non-arteritic Anterior Ischemic Optic Neuropathy

Objective1、 Discusses the characteristics of24hour ambulatory blood pressure in patientswith NAION2、 To investigate relationship between parameters of ambulatory blood pressuremonitoring and degree of vision decreased in patients with nonarteritic anteriorischemic optic neuropathy (NAION).Materials and methods1、 object of study1.163patients corresponded to the diagnosis criteria for NAION were involvedinto the study. According to visual decline degree, all patients were divided into lowvisual group and better visual group and into double eyes group and single eye group.1.2Choose the persons without NAION were enrolled in the study.2、methods2.1Conforms to the patients with NAION diagnosis, and no obvious retinalpathological changes.2.2The U.S. Suntech Oscar2noninvasive portable blood pressure monitor wasused for24hour blood pressure monitoring. The parameters of dynamic blood pressureparameters were recorded.2.3Analysis on dynamic parameters of blood pressure, described blood pressurecurve type, calculated blood pressure variability, Morning blood pressure surge, andheart rate variability.3、statistical methodUse CHISS statistical software for data analysis. Paired T test was used for compare the two groups with measurement data. The enumeration data were described by percentage and chi-square test was used for compare. P<0.05was stat istically significant.Result1、(1) The average24hSBP, nSBP and nDBP in the patients with NAION werehigher than the patients non-NAION.(2) The lowest nDBP in NAION group werehigher than control group. The decreasing rate of blood pressure at night in NAIONgroup was constantly lower than in control group.(3) The rate of dippers type curve inNAION group was lower and the rate of reverse-dippers type curve in NAION groupwas higher. The both differs were statistically significant.2、Compared with the control, the BPV of24hSBP, dSBP and dDBP wassignificantly increased. The MBPS was rare in NAION. The average HR and variabilityof HR were usually normal in NAION.3、The diastolic blood pressure of the night in double eyes group was higher than insingle eye group. The age in low visual group was older than in better visual group. Theincidence of abnormal circadian rhythm of24-hour ambulatory blood pressure wassignificantly higher in low visual group than in better visual group.Conclusion1、The prevalence of abnormal circadian BP rhythm was quite high. The nighttimeSBP and DBP not properly decline may one of the pathogenetic factors of NAION.2、Abnormality of BPV in patients with NAION is common, especially in daytime.The rise of blood pressure at morning was slightly. It is necessary refer to result ofABPM and take an individual therapy to NAION.3、In terms of NAION the patients with onset older and abnormal circadian rhythmof ambulatory blood pressure more likely to suffer poor visual acuity and higher risk ofdouble eyes involved.