| Objective: To investigate regional ventricular long-axis velocity andadjacent intraventricular flow velocity using dual-PW Dopplerechocardiography synchronously, and to analyze the coupling relationshipbetween regional ventricular long-axis strain and adjacent intraventricularpressure gradients in normal cases using dual-PW Doppler echocardiography.Methods: Eighty-six normal subjects aged19～66years （mean age37.49±11.97years） underwent routine echocardiography and dual-PWDoppler echocardiographic exam. Total18segments were sampled usingdual-PW Doppler （PW/TDI mode） images at basal, mid and apical levels onthree standard apical views, and electrocardiogram was recordedsimultaneously. Peak early diastolic velocity（emax）, peak late diastolicvelocity（amax）, peak early mitral diastolic inflow velocity （Emax）, regional peakearly diastolic velocity （Em）, regional peak late diastolic velocity （Am） andregional peak early diastolic inflow velocity （E） were measuredsimultaneously in the same one cardiac cycle. Myocardial variations of leftventricular segments were observed. Em, Am and E of different levels fromdifferent ventricular wall were analyzed. The co-relationship betweenregional ventricular long-axis strain and adjacent intraventricular pressuregradients were calculated and analyzed.Results: （1）Regional myocardial velocity and regional peak early diastolicinflow velocity in normal subjects declined from basal to apical segmentsgradually at the same ventricular wall（P<0.01）.（2）Emaxwas correlated with emax（r=0.418, P<0.001）, and E wascorrelated with Em （posterior septum, r=0.610, P<0.001; anterior wall,r=0.499, P<0.001）.（3）There was a medium correlation between normal long-axis strain insegments and adjacent intraventricular pressure gradients （the global, r=0.412,P<0.001; posterior septum, r=0.319, P<0.005）.Conclusion：The acquirement of E and Em by dual-PW Dopplershowed downtrend of segmental wall movement and regional blood flowfrom basal segment to apex. Emaxis correlated with emax, E is correlated withEm, and long-axis strain at segments is correlated with adjacentintraventricular pressure gradients partly. Dual-PW Doppler might provide apotential method for the more precise evaluation of left ventricular fluid-solidcoupling during diastole. |
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