Studies Based On The Epidemiology Of Senile Dementia Pathogenesis

Objective：This paper through the combination of senile dementia ancient and modern literatureresearch and epidemiology method, the use of statistical methods of data mining analysis,and to explore of senile dementia etiology and pathogenes studies new ways and new law.Methods：First, the use of philology, the collection of ancient and modern literature, systemanalysis of senile dementia the nonaggressive History, etiology, pathogenesis, commonsyndromes and symptoms, to extract from the overall understanding of the law ofdevelopment of the etiology and pathogenesis of this disease, and for the future of thepopularThe study provides the basis of philology.Stratified random sampling method using popular school Yingze Wanbailin DistrictXinghualingqu more than60-year-old male and over the age of60postmenopausal womenresident population carry senile dementia neuropsychologicalscreening cases of Chinesemedicine syndrome four diagnostic analysis of the etiology and pathogenesis, throughstatistical analysis of survey data, summarize TCM syndrome pathogenesis of differentpathological stage of the disease evolution and risk factors and syndromes classification.Results：1.Ancient literature etiology and pathogenesis combing results(1) Ancient physicians’ etiology of this disease usually caused by "shock, fear, anxiety,phlegm."(2) the understanding of the basic limitations of disease location in the two dirty---liver and kidney.(3) pathogenesis of "yang hyperactivity or Huo, phlegm, qi deficiency, blooddeficiency, qi stagnation, gas chaos."(4) the evolutionary law among of disease location, etiology, pathogenesis, syndromeis: the frightened, fear, excessive anxiety, or phlegm condensation on the inside, causingthe impassioned internal injuries, straight in the organs or lead to qidisorders, resulting in "qi stagnation”, even" gas chaos ", stagnation lead to heat, andzlong time produce phlegm turn to" yang hyperactivity "and" phlegm ", liver andkidney injuries. 2Results of epidemiology etiology and pathogenesis(1) screening out high-risk factors: women, senior citizens, manual workers (workers,peasants), widowed, living alone, low education level, family history of cerebrovasculardisease, preferences of meaty dishes and sweets, smoking, alcohol consumption and thedisease is closely related.(2) determine the position from disease dementia mainly in the kidney (50.0%),spleen (48.4%), heart (43.4%), disease located in the liver (29.2%), lung (7.5%) of thesmall.(3) from the deficiency disease screening machine, yang, blood, internal wet, bloodstasis is the most common disease syndrome factors.(4) Statistical results dementia nine syndromes descending order were: reducedkidney marrow, heart and spleen deficiency, spleen and kidney deficiency, kidney and liveressence deficiency,qi stagnation and blood stasis, phlegm block, heart and liver yindeficiency, wind phlegm orifices network, hot junction organs fact.(5) the etiology and pathogenesis evolutionary law can be divided into sevencategories:"Kidney–Qi deficiency–Yang deficiency-sperm loss type","heart andspleen-blood deficiency type","Liver-qi stagnation–Yin deficiency-type","lung-Qistagnation and blood stasis type "," wind-cold-scrambling god type "," Yang Kang-firedry type "," phlegm-retraction type."3Other epidemiological findings(1) The prevalence of dementia in Taiyuan area compared to the overall level ofdomestic slightly lower overall prevalence rate reached6.36%, which reached3.1percentof Alzheimer’s disease, vascular dementia, accounting for2.86%, with mixed dementia0.4%.(2) the SD ancient and modern understanding of the etiology and pathogenesis ofroughly the same, but slightly different. May be associated with modern livingenvironment, nature of work, partial addicted to diet, social pressures and changes inhuman gene.(3) Taiyuan area is same with SD risk factor of modern medical understandingroughly, but slightly different. May be related to geography, diet, living habits, differentideas about the crowd. (4)"liver","blood deficiency","shock", the judgment dementia AD, VD, MD degreecontributes the most among three types of elements.(5) Support of AD symptoms have seven terms,namely: walk, easy shock and fear,looking lusterless, dull, urine hot, dry stool, moss cloud. Support VD/MD are seven,namely: eccentric action, speech obscure, head tingling, vertigo, hemiplegia, urinaryincontinence, stool from the left; syndrome factors Table Analysis: Fire is discriminatingAD and VD/MD important indicators; risk factors analysis: family history ofcerebrovascular disease was slightly higher in the group of AD patients with VD/MDcompared differences.Conclusion：1. ancient literature on dementia understanding is progressively, from scattered tosystem, the ancients understanding of pathogenic risk factors is still relatively vague, donot form a valuable insight.2. ancient Pathogenesis evolution is: the frightened, fear, excessive anxiety, or phlegmcondensation on the inside, causing the impassioned internal injuries, straight in the organsor lead to air malfunction, resulting in "qi stagnation ’, very." air chaos ", Yu and heat, longand phlegm, to" wang yang hyperactivity or "and" phlegm ", liver and kidney injuries.3The prevalence of dementia in Taiyuan and other domestic epidemiological surveycoincide.4Epidemiological studies pathogenesis evolution can be divided into seven categories:"Kidney-Qi-Yang-sperm loss type","Heart-deficiency type","Liver-air stagnation-yin deficiency type "" lungs-blood stasis type "," wind-cold-scrambling god type ","Yang Kang-fire dry type "," phlegm-retraction type."5By comparing different ancient syndrome elements, obtained the survival differencemay be related to the modern environment, nature of work, partial addicted to diet, socialpressures and changes in human gene related.6Comparison of Taiyuan area and modern epidemiological survey of senile dementiarisk factors may be associated with different results in this area of Taiyuan, north Chinadiet, living habits, different ideas about the crowd.