The Clinical Value Of The Fraction Exhaled Nitric Oxide In Children With Mycoplasma Pneumoniae Pneumonia

Objective: To determine the value of the fraction exhaled nitric oxide(FeNO)measurement in children with Mycoplasma pneumoniae pneumonia(MPP).Methods:122inpatients with low respiratory tract infection were enrolled fromAugust to November in2012,69patients had MPP and33revealed an etiology other thanMycoplasma pneumoniae(MP). patients with MPP were further grouped intobronchopneumonia group and lobar pneumonia group.24outpatients diagnosis ofbronchial asthma were enrolled as asthma group,54inguinal hernia patients withoutrespiratory tract infection during the last two weeks were enrolled as control group. FeNOis measured by nitric oxide analyzer(NIOX Aerocrine AB Solna Sweden). eosinophile wasdetected by blood cells analysator.Results:(1) the level of FeNO in patients with MPP was lower than control group(P<0.0001). the level of FeNO between patients of non-MPP and control group had nodiscrepance (P>0.05). the level of FeNO in asthma group was higher than control group(P<0.0001).(2) the level of FeNO in patients with MPP was lower than the non-MPPgroup(P<0.0001). the level of FeNO between bronchopneumonia group and lobarpneumonia group with infection of MP had no discrepance (P>0.05)..(3) the proportion of blood eosinophile in patients with MPP was lower than non-MPP group(P<0.0001).Conculsion: Mycoplasma pneumoniae pneumonia may induce to a low level ofFeNO because of airway inflammation. FeNO measurement would be helpful as an idealand effective non-invasive inflammatory inspection method in the assessment ofMycoplasma pneumoniae pneumonia.