| Background: At present, the incidence of chronic kidney disease(CKD)increased year by year, what will inevitably progress to end-stage kidneydisease (ESRD).Because of the causes of ESRD are very diversity, the patients’condition is complex,and the complications are severe, although dialysis as atreatment for ESRD has saved many patients’ lives, there are still a highproportion of dialysis patients die of dialysis complications.For these reasens,how to better choose dialysis way has always been a problem of the medicalprofession at home and abroad.Objective： Observe and compare the curative effect betweenhemodialysis(HD) and continuous ambulatory peritoneal dialysis(CAPD)onESRD. Improve the quality of life of patients with ESRD, to provide bettertreatment for them, and reduce the hospitalization rate and mortality. accordingto the way to dialysis, patients were divided into hemodialysis group andperitoneal dialysis group.Materials and Methods: A retrospective analysis of96patients withESRD who has entered to our hospital urology department for treatment fromJanuary2010to December2012. Before and after dialysis, compared thegeneral information, general condition， the improve of the renalfunction,biochemical indicator and complications between two groups. Results:(1)The age, sex and etiology of patient’s between two groups was noobvious difference.(2) At the beginning of dialysis, the body weight, urine volume and blood pressure between the two groups were no significantly difference.After1year dialysis, the urine output in both groups were gone down,HD had significant difference as CAPD had none. Comparison between the two groups have significant differences. Two groups of blood pressurewere relatively decreased before dialysis, At the systolic blood pressure,CAPD decreased significantly more than HD.(3)The improve of the renal function: compared to beforedialysis, the serum creatinine, blood urea nitrogen toxin levels are both reduced（P＜0.05），But calculating glomerular filtration rate, HD group was(6.55±0.97) ml/min and CAPD group was (7.57±1.14) ml/min, two groups wassignificant difference (P <0.05), indicating that CAPD is conducive to theprotection of the residual renal function；(4)Biochemical indicators：The two groups after treatment, the level ofHb、TG and TC of CAPD group was higher than the HD group, the differencewas significant (P <0.05)；and the level of TP and ALB in HD group washigher than CAPD group, there was significant difference (P <0.05).(5)Hypertension、congestive heart failure and arrhythmia in the HDgroup was obviously higher than that of the PD group (P <0.05); And compared with HD group, infection and malnutrition was more in PDgroup,there was significant difference (P <0.05).Conclusion:1、After one year treatment,compared with HD,CAPD can protect residualrenal function better and delay the deterioration of kidney disease.2、In the curative effect of renal anemia, CAPD is better than HD.3、Two types of dialysis for the influence of calcium and phosphorus didnot see obvious difference, but for the removal of the PTH,CAPD is better.Socompared with HD,which is easier to occur cardiocerebral events,CAPD has asuperior security.4、CAPD had more disorder of lipid metabolism than HD.5、HD could Correct hypoalbuminemia more good,the incidence rateof infection was lower than CAPD.We should pay attention to individual, according to each patient’s specificsituation to choose the way to dialysis. |
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