Clinical Study Of Biofeedback Combined With Zhitong Rushen Decoction Fume-cleansing To Treat Functional Anorectal Pain

Objective:To observe the clinical efficacy and safety of the biofeedback combined with zhitong rushen decoction fume-cleansing to treat functional anorectal pain.Methods:All the subjects were outpatients or inpatients of the Second Affiliated Hospital of Hunan University of Tranditional Chinese Medicine in2011.2-2013.2, a total of80cases.The patients collected were divided randomly into4groups, each group of20cases. The four groups of patients in disease duration,age,gender and pain score before treatment have no statistical significance(P>0.05), with comparable. The treatment group are trained with biofeedback therapy apparatus (Thought-Technology Myotrac3)firstly, and then the zhi tong rushen Decoction(Guangdong party Pharmaceutical Co. Ltd)fume-cleansing; The first control group are treated with biofeedback instrument training only; The second control group are treated with Zhitong rushen Decoction fume-cleansing only and the third control group are treated with diclofenac sodium suppositories(Hubei Dongxin Pharmaceutical Co.Ltd)anal. Observe the clinical efficacy and safety of the four groups, and regular follow-up.Results:After treatment the treatment group were lower than the control group in the pain visual analog scores (VAS), the difference was statistically significant (p<0.05).The clinical efficacy of the treatment group were better than the three control groups (P<0.05).Pelvic floor surface EMG assessment shows that:all the groups’s amplitude of contraction are higher than before treatment (P<0.05), but no significant differences between the two groups (P>0.05). the compare of coefficient of variation in Intermittent contraction and sustained contraction phase:between the groups,the treatment group and the1st control group had significant difference (P<0.01), the3rd control group was statistically significance of difference (P<0.05), the2nd control group with no significant difference(P>0.05).The treatment group compared with the1st control group, the difference is statistically significant (P<0.05), compared with the2nd,3rd control group, it had significant difference (P<0.01), and no significant differences between the control groups (P>0.05), it explains that treatment group is better than control groups on CV. While there was no significant difference in adverse reactions and safety assessment between the four groups(P>0.05).Conclusion:Biofeedback combined with Zhitong rushen Decoction fume-cleansing to treat functional anorectal pain in the aspects of VAS score,pelvic floor surface EMG assessment and clinical efficacy is better than the single use of biofeedback and Zhitong rushen Decoction fume-cleansing,or diclofenac sodium suppository anal, and less adverse reactions, is a safe and effective method in treatment of functional anorectal pain.