Studies On The Warmly Invigorate Kidney-Yang Effect Of Semen Allii Tuberosi After With Rice Wine Solution

Semen Allii Tuberosi is the dry ripe seed of Alliium tuberosum Rottl, pungent and sweet in flavour, warm, acting on the Tonifying kidney, impotence Gujing. Its function is for impotence, waist and knee pain, enuresis frequent micturition, whitish down. There are two kinds of processed forms in " Pharmacopoeia"2010Edition, which one is’The Crude Seed Allii Tuberosi (CSAT)’, the other one is’The Salt Seed Allii Tuberosi (SSAT)’, CSAT is processed by excluding impurity, and SSAT is stir-heating the CSAT with salt solution. CSAT and WSAT(the wine Seed Allii Tuberosi) are less application,clinical use of SSAT.ObjectiveThis paper selected Semen Allii Tuberosi as the research object is based on the differences in its processing method of historical background, and the task group made in-depth study on the SSAT with effect as the breakthrough point of the different processing methods on Semen Allii Tuberosi " warming kidney-yang". to clarify the ancient wine processing is the rationality of science, on main pharmacological activities of Semen Allii Tuberosi have its effect.as well as CSAT, SSAT> WSAT have no obvious change in in physicochemical properties, and preliminary study on the processing technology of WSAT in elucidating the efficacy of pharmacodynamic material basis.MethodsThe use of literature research, chemistry and pharmacology in combination with means to carry out Semen Allii Tuberosi processing research.1. Using the method of literature research, collate Semen Allii Tuberosi of ancient and modern processing methods and effect of Chinese medicine Chinese chive seed, elucidating the history and modern processing condition. 2. On the basis of the above research, development of Chinese chive seed wine processing technology research.3. Using pharmacological methods of Semen Allii Tuberosi, three kinds of processed products of Warming Kidney Yang efficacy of pharmacodynamics comparative study of Semen Allii Tuberosi, understanding of different processing methods on the effect of Warming Yang.4. Using chemical method, in effect as the guidance, screening of WSAT Warming Kidney Yang effective parts, and used as a comparative study of fingerprints of.Results1. The textual research results show that:the medical history of the emergence of numerous Semen Allii Tuberosi processing method for frying and wine fried up, relates to rice wine, vinegar and wine and dates of three kinds of processing accessories, visible frying is the mainstream method in ancient Semen Allii Tuberosi processing; now Semen Allii Tuberosi are salt roasting.2. Preliminary establishment of WSAT processing technology is:each100kg medicine joins55kg drinks (including10kg rice wine), at normal temperature and moistening after6hours at150DEG C with the container, with the40/min stir fry15minute frequency.3. Semen Allii Tuberosi having reduced kidney yang deficiency mice adrenal VC content in rats of kidney yang deficiency and prolonged cold dead time effect. The SSAT through the kidney yang deficiency mice after reducing the content of VC in adrenal action increases further, the WSAT after extended in rats of kidney yang deficiency cold dead time and increased mating ability increases further.4." Alcohol and water double stripping and ethyl acetate extract+wine" is WSAT’ warming kidney-yang" role in the effective parts; adopting HPLC technology for the parts of the fingerprint, and analyzed and some salt and wine and the chemical composition of the differences. ConclusionsSemen Allii Tuberosi has a certain temperature and recuperating the kidney-yang, different processing methods on its efficacy has certain effect, SSAT can further enhance the function of the adrenal cortex, WSAT can further improve the kidney yang deficiency mice cold-resistant ability and strengthening the kidney yang deficiency mice mating ability, that the ancients used frying and" wine paste for pills and salt soup send service " medication requires a certain degree of scientific rationality, rice wine of Semen Allii Tuberosi Warming Kidney Yang role with synergistic effect." Alcohol and water double stripping and ethyl acetate extract+wine" is wine fried leek seed" warming kidney-yang" role in the effective parts.