Bu Shen Huo Xue Method United Alendronate Prevention Of Postmenopausal Osteoporosis Efficacy Observation

Objective:This the subject is principle to Bu Shen Huo Xue method. Through observe the changes of bone pain and bone metabolic markers in postmenopausal osteoporosis patients treated by Bu Shen Huo Xue Soup dialectical addition and subtraction united Alendronate. And compare with Alendronate alone. To explore the ways of improving the efficacy of osteoporosis in postmenopausal,and to provide the experimental basis and value for Bu Shen Huo Xue Method prevention and Treatment of postmenopausal osteoporosis,Methods:Diagnosed by clinical examination for postmenopausal osteoporosis, low back pain patients and are willing to join the clinical trial,60cases of all, And randomly divided into test group (combination therapy group), control group (Alendronate group). Test group:According to syndrome type, treatment on Bu Shen Huo Xue Soup dialectical addition and subtraction united Alendronate; Control group:Alendronate treatment. Observed analgesic efficiency of different stages of after treatment; and enzyme-linked immunosorbent assay before treatment and after12weeks of treatment, B-ALP, BGP, TRACP, DPD, Cr. And do statistical analysis.Results:1, the test group after4weeks of treatment, analgesic total efficiency compared with control group (P<0.05), statistically significant;8weeks and12weeks of treatment, no statistically significant difference, but The absolute value of significant efficiency and total efficiency are still greater than the control group.2, the test group and control group before treatment, the B-ALP, BGP, and TRACP5b, DPD excretion rate, comparison,P>0.05, not statistically significant, indicating that the selected cases randomized reasonable, the two groups were comparable;3, the test group before and after treatment B-ALP comparison, P<0.05; BGP comparison, P<0.01,were statistically significant; and TRACP5b comparison, P<0.01; DPD excretion rate comparison,P<0.01, were significant difference;4, the control group before and after treatment comparison with the B-ALP, P<0.05, BGP comparison, P<0.01; and TRACP5b comparison, P<0.01,DPD excretion rate comparison, P<0.05, were statistically significant;5, the two groups after treatment B-ALP, BGP, comparison, P>0.05, nostatistically significant; and TRACP5b, DPD excretion rate, comparison, P>0.05, not statistically significant, but in absolute terms, the test group lower.Conclusion:1, Bu Shen Huo Xue Soup dialectical addition and subtraction united Alendronate treatment compared to Alendronate treatment, the two groups were able to effectively improve the patients with bone metabolic markers in postmenopausal osteoporosis, to maintain an appropriate degree of bone turnover, adjust the balance of bonemetabolism; Chinese medicine dialectical addition and subtraction united Alendronate treatment to relieve pain symptoms in patients with markedly faster and better, and from the biochemical indicators after treatment in absolute terms, both associated with more than a single Alendronate therapy has more advantages.2, Syndrome differentiation by Bushenhuoxue Method, can improve the overall function of the body organs, By means of Bu shen zhuang gu, improve microcirculation. And united Alendronate can effectively prevent and treat postmenopausal osteoporosis, especially in improving pain bone aspect.