The Analysis Of The Associate Factors In¹³¹I Therapy Of Graves’ Hyperthyroidsm

Objectives:To analyse the treatment effects for Graves’ disease and the relatedfactors, to investigate the clinical therapeutic effect and factors associated with therapeuticeffect in¹³¹I treatment of Graves’hyperthyroidism.¹³¹I treatment for complications ofthyroid diseases. Materials and Methods:495cases weresuccessfully followed up for atleast1year.To analyzed retrospectively,including gender、age、duration of the disease、serum T3、 T4level,mass of the thyroid、 serum thyroglobulin antibody（TGAb）、throperoxidase antibody（TPOAb）,the highest¹³¹I absorption rate、radioiodine dose、drugtherapy、thyroid receptor antibodies（TRAb）. Using SPSS17.0statistical software analyzesthe data, to find the factors which affect the¹³¹I therapy for Graves’ hyperthyroidismefficacy. Results: In495cases,183cure （37.4%） still hyperthyroidism120cases （22.6%）,hypothyroidism, and193cases （40.0%）. Total effective rate （cure and hypothyroidism）75.8%（375/495）. The clinical efficacy mainly associated with mass of thyroid、 gender、duration of the disease、serum T3level、TGAb、TPOAb,the highest¹³¹I absorption rate、radioiodine dose and the TRAb（P＜0.05）.Conclusions:¹³¹I treatment for hyperthyroidismis a simple, safe and effective method; one administration can get a higher cure rate. Thepreferred method can be used as the treatment of hyperthyroidism.mass of thyroid、gender、duration of the disease、TGAb、TPOAb,the highest¹³¹I absorption rate、radioiodine dose and the TRAbcan influence the clinical efficacy.¹³¹I therapy forhyperthyroidism complications also has a good effect.