Governance Vertigo Mixture Treatment Of Posterior Circulation Ischemic Vertigo (Hyperactivity,Blood Stasis Orifices Type) Clinical Research

ObjectiveTo study the clinical treatment of Governance vertigo mixture circulating cerebral ischemic vertigo (hyperactivity, blood stasis awakened type), to explore its mechanism of action from traditional Chinese medicine pathogenesis and Western pharmacology, clinical guidance carry out the work.Methods84cases met the inclusion criteria were compiled by odd and even numbers, in accordance with the order of the duration of hospitalization for the treatment and control groups.Both groups of static blood Xuesaitong powder for injection,200mg/5%～10%glucose injection slow drip, or0.9%normal saline250ml diluted1/day. Oral medication with flunarizine hydrochloride capsules5mg Aspirin100mg daily at bedtime.On this basis, the treatment group Governance vertigo mixture (abalone20g Gastrodia12g, Uncaria20g, white peony root20g, the bidentata20g, mountain gardenia15g, Pinellia10g, dried tangerine peel10g, Poria12g, Pueraria20g Alisma12g, the Scorpion6g, white silkworm8g, the Gentiana10g, chrysanthemum10g, licorice10g). Made by the Department of XiangYang hospital of TCM of Pharmacy bottled Pharmacy,200ml/bottle. Dosage:warm water delivery service, each100ml/time, twice a day.The treatment lasted two weeks. Observing the clinical efficacy before and after treatment, physical and chemical indicators (blood lipids, blood rheology, transcranial Doppler) and TCM symptoms, signs of change in the situation and make statistical processing.Result(1) The clinical therapeutic effect:total efficiency of95.24%; the control group, the total efficiency of78.58%. Ridit test between the two groups, P<0.05, two groups with significant differences. Prompt treatment group than the control group.(2) physical and chemical indicators of observation:Lipids:the two groups after treatment (TC), TG and LDL-C has a significant statistical difference (P<0.05); treatment group lowering of TC, TG and elevated the role of HDL-C, compared with the control group, significant difference (P<0.05). Tip:Governance vertigo mixture can effectively regulate blood lipid content.Hemorheology:After treatment, whole blood viscosity, plasma viscosity, hematocrit, fibrinogen improved than before treatment, and treatment of whole blood viscosity, fibrinogen improvement is better than The control group (P<0.01, P<0.05).Intracranial hemodynamics:the treatment group compared with the control group before treatment, the VA, BA, Vs and Vm and PI, no significant difference (P>0.05), After treatment, the VA, BA Vs and Vm and PI significantly better than before treatment (P<0.05, P<0.01), suggesting that the two groups can improve intracranial hemodynamics; treatment group and control group after treatment, VA, BA Vs and Vm and PI compared, significant differences (P<0.05), indicating that the treatment group than the control group in improving cerebral vascular(3) TCM Syndrome:the two drugs in the improvement of traditional Chinese medicine the main symptoms, signs and tongue and pulse, a significant difference (P<0.05), suggesting that the rule halo mixture can effectively improve vertigo symptoms, signs.Conclusion:Governance vertigo mixture can effectively improve the posterior circulation ischemic vertigo in patients with clinical symptoms, signs, and physical and chemical indicators, suggesting that the efficacy of Governance vertigo mixture, is worthy of clinical application.