| This article discusses the animal experiments to verify the feasibility of the laser welding of common bile duct, seek a safer, more efficient, less trauma, convenient operation of the new technique.Experimental simulation of common bile duct exploration, in24experiments using dogs as the experimental object, take a random distribution principle of equally divided into two groups:control group (suture), the experimental group (laser welding group).Operation steps:open common bile duct under direct vision, respectively, using a suture or the method of laser welding repair of incisional, recording the operation time, intraoperative measurement of outer diameter and inner diameter of common bile duct.After first~5days after operation, the cavity through the drainage tube observed in the presence of bile leakage.Regular postoperative blood for detection of AST, ALT, ALP, at6months after operation. All of experimental dogs, measurements of suture at the CBD of outside and inside diameters, and the liver tissue pathological examination..Suture group after first to5days of bile leakage probability (2/12) and experimental group (3/12) there is no obvious difference between the.The control group of intraoperative suture time (15+2min) more than the experimental group (5+1min), contrast before and after the operation of bile duct diameter changes, suture group is3+0.5mm3.6+0.6mm group respectively, laser.Postoperative histology showed, the experimental group and the control group, CBD endometrial repair, inflammatory reaction, the formation of granulomas were the control group has the superiority, but in the change of liver function in liver damage, no obvious difference. |