The Computer Simulation On The Distribution Of¹⁰³Pd Radioactive Seed

According to the world health organization figures in recent years, more then5million people died of malignant tumor each year. Therefore, the malignant tumor has become one of the most important diseases which threaten human health. Radiotherapy is one of the four important cancer treatment methods, for the past few years the Radiotherapy has been broken through the’experience treatment age’gradually, but the accuracy of radiation treatment is still remains to be one of the most important research direction for improving radiation therapy effect. Bracytheraphy that is radioactive seeds implant treatment for cancer has been obtained a rapid development. Based on the quickly development of computer technology. In Bracytheraphy the dose distribution must be studied by Theoretical and experimental research In order to achieve the best treatment effect and make the dose to cover the tumor area entirely.The American Association of Physicists in Medicine (AAPM) TG-43and TG-43U1protocols has recommended some dosage calculation mode. According to the dosage calculation mode, the radial dose function had been fitted by Cftool toolbox which based on Nonlinear mathematical model theory in Matlab, and the anisotropy factor had been fitted by SFTool toolbox which based on Nonlinear mathematical model theory in Matlab, according to the optimum principle of fitting accuracy, The calculation of the radial dose function and the anisotropy factor result are obtained in an ideal situation, and then the dose calculation of single103Pd radioactive seed is determined, based on which the dose calculation mode of multiple103Pd radioactive seed is determined According to the linear superposition method. By using this mode the computer simulation of103Pd radioactive seed dose distribution has been gained. During the simulation, in order to Convenience In computer simulation, the paper used the Digital Image Processing in matlab to deal with the tumor CT image which contains enhance contrast, detection edge, extraction of tumor contour line and so on, this provide a new method for the processing of tumor CT image and offer a platform for the computer simulation of103Pd radioactive seed dose distribution.Based on the dose calculation mode of103Pd radioactive seed dose distribution, the computer simulation of103Pd radioactive seed dose distribution and the Tumor CT image processing, the software PDMD has been developed by matlab which can simulate the103Pd seed distribution conformably. By PDMD the dose rate for the Target Point of point103Pd source,single103Pd line source, multiple103Pd line source can be work out, and their isodose curves also can be obtained. What more the tumor contour line and the103Pd seed conformably distribution can be figured out.The PDMD is a graphical user interface Simple which Strong interactivity and simple, it is also appropriate for whatever radioactive seed besides103Pd when change some parameters. And this also provides new method for radioactive seed dose distribution for bracytheraphy.