Probe Into The Correlation Between Cholecystolithiasis(CHO), Cholecystectomy (CHE)and Colorectal Polyps And The Study Of TCM Body Constitution

Background:Cholecystolithiasis and Colorectal polyps are both common disease of the dig estive system. Cholecystectomy is one of the main treatment of Cholecystolithiasis. Cholecystoli thiasis, cholecystectomy has been considered one of the risk factors for colorectal cancer, colorec tal polyps, especially adenomas has been recognized as a precancerous lesion of colorectal cance r, but the relationship between cholecystectomy and colorectal polyps has not been taken seriousl y, Therefore, regular follow-up of patients with colorectal polyps have been referred to the preve ntion and control on the height of early colorectal cancer.Objective:Through research and review of clinical data of some colorectal polyps, discussi on on whether gallbladder disease (gallstones, cholecystectomy) and the colorectal polyps we re associated, use the Chinese medicine theory on which the adenoma in patients with physical ty pe, providing a new theoretical basis for the early detection of colorectal polyps in patients with gallbladder disorders and the endoscopic treatment, and also provide the TCM constitutions recu peration basis for the prevention and treatment of colorectal polyps.Methods:From the January2010to March2012in Jiangsu Province Hospital of Traditiona1Chinese Medicine, Digestive Endoscopy Center out-patient and ward,a total of400patients, ex cluded Inflammatory bowel disease,familial adenomatous polyposis (FAP),Peutz-Jeghers disease, cancer and other diseases by colonoscopy, according to the past with or without a history of cholecystectomy is divided into treatment group (82cases) and c ontrol group (306cases) randomly, analysising of the two groups of patients with colorectal p olyps the incidence of endoscopic the polyps performance and histological type.in addition, ident ificating the physical of74patients with polyp recurrence in these cases according to the TCM c onstitution classification criteria. These are used in Microsoft Excel to establish a database.and to use spss17.0statistical software to analyze.Results:Cholecystectomy group of colorectal polyps rate was higher than control group (42.7%to27.8%),and it has statistically significant difference (OR=1.936,p=0.01<0.05) Location and morphology of the two groups of patients with polyps were no significant differences (p﹥0.05). However, the risk of adenomatous polyps in patients with cholecystectomy was sig nificantly higher (or=2.729,p=0.028﹤0.05).Also,the survey found that there are several common physical types of adenomatous colorectal polyps:phlegm, damp-heat, blood stasis,Qi stagnation, Qi deficiency, Yang deficiency,Yin deficiency,gentleness and special intrinsic quality.Among these nine types,t here was,31cases of phlegm,25cases of damp-heat,4cases of blood stasis,3cases of qi stagnati on,5cases of qi deficiency,7cases of yang deficiency,0cases of yin deficiency,1case of gentless,1case of special intrinsic quality.Conclusion:1.The risk of patients with gallbladder disorders getting colorectal polyps has no nec essarily linked to cholecystectomy.2. The incidence of adenomatous polyps of Cholecystolithiasis was significantly higher;3. Cholecystolithiasis,Cholecystectomy is one of the risk factors for the incidence of colorec tal polyps;4. Among those common physical types of adenomatous colorectal, phlegm,damp-heat, sign ificantly higher than other constitutional types, accounting for80%of the patients;5. Emphasising on screening and monitoring the early colorectal cancer and adenomatous p olyps of patients with cholecystectomy postoperative is necessary.