The Relationship Of In-hospital Patients In Sudden Death With Acquired Proloned Q-T Interval

Objective:Risk factors and treatment options of patients with suddendeath because of acquired proloned Q-T interval are smmarrized in this study.Methods:Using"cardiac arrest",’’cardiopulmonary resuscitation’’ and’’sudden death’’ as the keywords to search the inpatient database from2006-2011of First Affiliated Hospital of Guangxi Medical University.Results:1.53eligible patients were included in this analylsis.,the meanQ-Tc was492±32ms and442±42ms before and after treatment.2. Structuralheart diseases were found in35.8%, cerebral vascular accident was found in22.6%, pneumonia was found in18.9%, gastrointestinal hemorrhage was foundin11.3%.3.electrolyte disorders in28.3%patients，before potassium supplementK~+(2.98±0.65) mmol/L,after potassium supplement K~+(3.84±0.55)mmol/L,20.8%patients received diuretic therapy and5.7%receivedchlorpromazine or antiarrhythmic drugs which might induce prolonged Q-T interval，In addition, there were12patients revealed no cause.4.The definitivediagnosis of acquired Q-T prolongation syndrome disease targeted treatment in7cases.Emergency cardiopulmonary resuscitation of41cases,31cases ofadrenergic, tracheal intubation in24cases,10cases of electric defibrillation,inresponse to pacing in treatment of2cases，the success rate of83%.Conclusion: Acquired Q-T interval prolongation may be the importantcauses of sudden death in patients in hospital and hypokalemia is the main causeof acquired Q-T interval prolongation. Understanding insufficiency of acquiredproloned Q-T interval in general ward is prevalent, we can improve the successrate of treatment as long as strengthen the monitoring and targeted treatment.