| Objective To observe the clinical curative effect and blight of the formula which calming the liver and eliminating phlegm to treat the acute phase of ischemic stroke. Evaluates its validity and security of treating the acute phase of ischemic stroke, and discusses its function mechanism initially, to provide the beneficial reference for clinical treating the acute phase of ischemic stroke.Methods All cases illness which admitted to the brain branch ward in the Chinese medicine hospital in Wuhan City from May,2011to March,2012, conformed to the diagnosis standard of ischemic stroke, who were differentiated as apoplexy involving the meridians(the Wind-phlegm and hyperyang syndrome or the Wind-phlegm stasis syndrome), all together68examples, divided into the treatment group and the control group. The treatment group35examples, used the formula coordinating conventional western medicine to treat just right for the illness; the control group33examples, used the conventional western medicine to treat just right for the illness. When necessary two groups given the abdominal Puncture to extract ascites for treatment of reducing pressure. Two weeks were a treatment course, a total of two courses of the treatment.Recorded the main symptoms, a time respectively before and after the treatment and the complication situation after the treatment and then made the traditional Chinese medicine symptomatology integral evaluation. Following symptoms were taken into the evaluation, such as alteration in consciousness (normal as0point, sleepiness as3points, Taoism as5points, coma as7points, dote as9points), oral expression(normal as0point, dysarthria as1point, sentence-breaking as3point, vagueness as4point, aphasia as6point), facial paralysis (no paralysis as0point, slightly paralysis as1point, completely paralysis as1point),other symptoms such as hemiplegia, limb numbness, dizzying, tinnitus, headache, limb clonus and rigidity, irritability, abundant sputum, dry mouth, polypnea and debility, were divided into4degrees, as normal, slightly abnormal, moderately abnormal, Severe abnormal, respectively recorded as0,1,3,5point. Recorded the NHISS score, a time respectively before and after the treatment; observed the general medical examination for the body(for example T, P, R, BP), blood routine test, urine routine test, Stool routine test,the liver and kidney function, the electrocardiogram and untoward effect a time respectively before and after the treatment, marked the secure appraisal. After the observation had ended, possessed all the data to carry on the statistical analysis. The measurement data used the mean value±standard deviation x±s to carry on the statistical description, the measurement data used the T-test, the counting data used the chi-square-test. P>0.05had the non-significance difference, P<O.05had the significance difference, P<0.01had the unusual significance difference. To explore formula which calming the liver and eliminating phlegm with Western Medicine measures to deal with the clinical symptoms, neurologic impairment is superior to simple symptomatic treatment measures to deal with.Results1. The cases selected:the treatment group had2shed off because of lose to visit, the control had l,the expulsion rate was5.41%of the treatment group,2.94%of the control group, without rejected cases. There were68patients (35of the treatment group,33of the control group) treated completely to press the research project for2weeks,35of the treatment group,33of the control group, carrying on respectively with follow-up visit for2weeks.2.synthetic therapeutic effect and traditional Chinese medicine syndrome therapeutic effect in clinic:2weeks after the treatment, comparing synthetic therapeutic effect in clinic, for the treatment group, the excellence rate was57.14%, the total effective rate was88.57%, for the control group, the excellence rate was30.30%, the total effective rate was66.67%, protocols of the treatment group to deal with the clinical symptoms, neurologic impairment is superior to that of the control group, there were significant difference between two groups (P<0.05).Conclusion Clinical observation shows that:(1) Treatment group used in the treatment of acute phase of ischemic stroke prescription efficacy of certain patients dealing with the clinical symptoms, neurologic impairment, is better than the control group, and reduced the occurrence of various complications, patients with reduced pain, improved survival in patients with quality, and security, economic, and clinical treatment of acute phase of ischemic stroke, we provide a useful reference.(2) Formula which calming the liver and eliminating phlegm with Western Medicine measures to deal with the clinical symptoms, neurologic impairment is superior to simple symptomatic treatment measures to deal with. When formula which calming the liver and eliminating phlegm improve the clinics symptoms, it can also to relive the patients economic tension and the complication such as bleed and pulmonary infection to establish the curative effect foundation in the long time. |