Acupuncture Four Joint Points On Spleen Stomach Deficiency Type Of Infantile Anorexia With Leptin Levels In Rats

ObjectiveInfantile anorexia nervosa (advance of infantile) refers to the pediatric longer anorexia or loss of appetite, seeing food is not corrupt, even eating, eating less, is a chronic digestive disorder syndrome, is a common pediatric diseases, frequently-occurring disease [1],1～6years old children to see more, and have rising trend year by year, city higher prevalence in children. If the duration of delayed healing, can make blood metaplasia spent source, droping of disease-resistant ability, with his disease, can lead to malnutrition, anemia, rickets in children and immunocompromised, appears repeatedly respiratory infection, on the growth and development of children, nutrition status and intellectual development has different effects. Current treatment of Western medicine, the effect is not ideal, and traditional Chinese medicine in the treatment of infantile anorexia has excellent curative effect, less adverse reaction advantage. In recent years, the modern medicine on serum leptin and anorexia related conducted in-depth research, leptin is secreted by fat cells is a protein hormone, on appetite and energy metabolism plays an important role in the regulation of leptin action in the hypothalamus, the POMC system synthesis increases, which causes a series of physiological responses、loss of appetite and increase energy consumption and sympathetic increased neuronal excitability, and when leptin levels drop, role of leptin in the hypothalamus that neuropeptide Y synthesis, secretion, via Y5receptors, the body produces corresponding responses, i.e., increased appetite, parasympathetic function increases, the energy consumption is decreased, lower body temperature, thereby restoring the fat volume. From ancient times to the present four slit acupoint on acupuncture treatment of infantile anorexia by acupuncture has good effect, four joint points on anorexia in children serum leptin in the rat, discusses the use of the method in treatment of anorexia in children is effective and the change of serum leptin levels and correlation, and its clinical application to lay the theoretical foundation.MethodThe test of eligible subjects are divided into two groups:treatment group (acupuncture four aperture), control group (normal children), according to the programme for research, treatment group (acupuncture four aperture) in15cases, control group (15cases of normal children), acupuncture four aperture on children appetite, food intake and patients before and after treatment, serum leptin levels and leptin levels compare to normal children’s, statistical analysis, and then discusses the method for treatment of infantile anorexia effectiveness mechanism.Achievements①The acupuncture four seam points for treatment of infantile anorexia due to insufficiency of total efficiency is86.7%. Patients are before and after treatment, the main symptoms of the total, before treatment and after treatment of food intake, appetite integral comparison difference has statistics significance (P＜0.05);②The treatment group before treatment and serum leptin level in serum leptin levels compared to normal children’s (the same sex) are statistically significant (F:P＜0.01),(M:P＜0.05);③The treatment group after treatment with serum leptin levels and serum leptin levels compared to normal children’s (the same sex) are not statistically significant (F:P＞0.01),(M:P＞0.05);④The patients before and after treatment, serum leptin levels compared to (the same sex) are statistically significant (F:P＜0.05),(M:P＜0.01).ConclusionLeptin as a mainly secreted by adipose cells, with important biological activity of multiple skin type of hormone, in the regulation of appetite and energy metabolism play an important role in the process. Acupuncture four aperture can significantly improve the children’s appetite, food intake and other major symptoms, so that in vivo leptin level change, so close to the children with normal serum leptin levels, so as to control appetite and energy consumption, improve the symptoms of anorexia.