Clinical Research On The Correlation Of Ultrasonic Feature And Liver Function Grade Of Post-hepatitis Cirrhosis Between Different TCM Syndromes

Objects:Viral hepatitis is the main cause of cirrhosis in China. There are many hepatitis B virus infections and prevention and control situation in this disease is particularly severe, cirrhosis patients often died of the severe complications, prognosis is poor. Ancient literatures of traditional Chinese medicine have detailed discourse on common signs and symptoms of cirrhosis and have different view on its etiology, pathogenesis, syndrome diagnosis and treatment. Modern medical ultrasound plays an important role in diagnosis, etiology, judgment and condition assessment of cirrhosis, and has a lot of recent progress. This clinical research based on Summarized Review of ancient literatures of TCM and modern ultrasound progress related literatures, according to the clinical epidemiology thinking, study on the correlation of ultrasonic feature including morphology data of liver, gallbladder, spleen and hemodynamic data and CTP classification, MELD score of cirrhosis after hepatitis between different TCM syndromes Preliminarily, so as to discover Valuable ultrasound parameters on TCM syndrome discrimination. This will give new meaning to traditional Chinese medicine syndrome differentiation of liver cirrhosis and explore new ideas on its prognosis.Methods:According to uniform standards, take syndrome differentiation on patients that meet the inclusion criteria, and take ultrasound of abdomen and the portal vein system, improve other laboratory tests, determine liver function CTP classification and the MELD score, completing the post-hepatitis cirrhosis clinical observation record sheet. Using EXCEL for data entry, establish a database, using the SPSS17.0statistical package for data management and statistical processing. Using descriptive analysis, two independent samples t-test was used to compare the two groups; count data rate, proportion between the two groups were compared using the X" test. This study collected135cases of qualified hepatitis B cirrhosis patients in five hospitals in Beijing. Results:Yin deficiency of Liver and kidney, Yang deficiency of spleen and kidney and blood stasis syndromes take majority in advanced cirrhosis patients compared with liver Qi stagnation syndrome and dump-heat accumulation syndrome.The narrowing trend on left hepatic lobe vertical diameter is obvious and spleen increased more significantly, more prone to have imbalance lobe of the liver form, the liver capsule jagged, increased diffuse echoes, gallbladder wall, thickening, extent of the portal vein congestion also increased, the inner diameter of the trunk gradually widened, and portal vein blood flow is increased gradually and blood flow slow down.The left hepatic lobe vertical diameter may be suitable for prompt indications for judgment of blood stasis syndrome type in cirrhosis and we may Judge Yin deficiency of Liver and kidney, Yang deficiency of spleen and kidney and blood stasis syndromes in accordance with imbalance lobe of the liver form, the liver capsule jagged, increased diffuse echoes.Gallbladder wall thickening may be suitable as one of the reference on judgment of moisture resistance syndrome, Yang deficiency of spleen and kidney syndrome and blood stasis syndrome of the hepatitis R cirrhosis.Gallbladder cavity echo inequality and the gall bladder wall rough may be the indication of dump-heat accumulation syndrome.Maximum oblique diameter, the right lobe, right lobe of the anteroposterior diameter of the left hepatic lobe anteroposterior diameter, nodules or grid-like echo the incidence of gal istone incidence of bi lateral levy incidence and ascites depth may not be appropriate as reference on TCM syndrome judgment of the hepatitis B cirrhosis.Portal vein diameter, and portal vein blood flow velocity, portal vein congestion index may be appropriate as reference on TCM syndrome judgment of Yang deficiency of spleen and kidney syndrome and blood stasis syndrome of the hepatitis B cirrhosis, as the inner diameter of the trunk gradually widened, and portal vein blood flow is increased gradually and blood flow slow down.Splenic vein flow velocity parameters may not be appropriate as reference on TCM syndrome judgment of the hepatitis B cirrhosis.The liver function CTP classification in liver Qi stagnation syndrome and dump-heat accumulation syndrome patients mainly scores to Class A,and the MELD score less than10points-based. The liver function CTP classification in Yin deficiency of Liver and kidney, Yang deficiency of spleen and kidney and blood stasis syndromes mainly scores to Class B-C,and the MELD scores more than10points basically.Yin deficiency of Liver and kidney, Yang deficiency of spleen and kidney and blood stasis syndromes take majority in advanced cirrhosis patients compared with liver Qi stagnation syndrome and dump-heat accumulation syndrome take majority in early stage cirrhosis patients.