Analysis Of Chest CT Appearances Of Microscopic Polyangiitis In Different Stages

Objective:To evaluate the clinical application of chest CT in the diagnosis of Microscopic polyangiitis (MAP).Methods:Clinical data and chest CT images had been collected from46patients in whom MAP was eventually diagnosed. Depending on their clinical manifestations, the46cases fell into2groups, the active group and the stable group. And then contrast statistical analysis was made.Results:In the46studies,34of46patients in active group and12of46patients in stable group.1, Chest CT manifestations of the46cases with MPA:①Ground glass opacities in28cases(60.9%):24cases in active group and4cases in stable group.②Lung consolidation in16cases (34.8%):all cases in active group. Pathological changes were inclined to be found in middle and inferior lobe of both sides.③Scattered patch shadow in22cases (47.8%):19cases in active group and3cases in stable group. It can be found in either or both side with no characteristic feature in distribution.④Cordal and reticular shadow in33cases (77.7%):23cases in active group and10cases in stable group. It was more often found in middle and inferior lobe of both sides as well as the peripheral and subpleural area.⑤Honeycombing changes in6cases(13.0%):5cases in active group and1case in stable group. It tended to be found in middle and inferior lobe of both sides.⑥Pleural effusion in23cases (50.0%):22cases in active group and1case in stable group.⑦Emphysema in8cases (17.4%):7cases in active group and1cases in stable group.⑧Mediastinal lymphadenectasis in25cases(54.3%):23cases in active group and2cases in stable group.2、Contrast analysis of CT manifestations of MAP between the two groups: appearances of lung consolidation, ground glass opacities,、mediastinal lymphadenectasis and pleural effusion in the active group are more commonly found than in the stable group, and the difference between the two groups shows statistically significant difference(P<0.05); otherwise appearances of fibrio-reticulation、scattered patch shadow、honeycombing change and bulla can be found in both groups, the difference between the two groups shows no statistically significant difference(P>0.05).Conclusion:Chest CT appearances of MPA in different periods have different characteristics, so the chest CT scan can assist clinical diagnosis and it can guide the clinical treatment.