E Antigen In Blood Transfusion Of Blood Recipients Immune Function

Rational clinical transfusion of blood transfusion safety put forward as WHO is one of the threestrategy,More and more attention by people.Our country "clinical transfusion specification", putforwards conventional inspecting ABO blood group and Rh (D) blood type, Requirements arethe same type of infusion. In our work, we found that Rh (E) the proportion of patients withnegatie higher (25%30%). We’d like to know something about this aspects of the situation. Inour blood transfusion patient Rh blood group E antigen detection, Analysis for E antigennegative donor recipients E antigen positive, infusion of blood donors after by the body’simmune function have certain effect, We think, at the first blood transfusion when should notonly meet the blood mixed with, also should consider Rh factor, the factor of possible infusionRh factor as far as possible "completely blood composition, also can avoid the recall reactionby the late-occurred hemolytic transfusion reactions. For more safety after the blood transfusion,provides the basis.The paper does not cross matching blood clots, Irregular antibody ofnegative by blood donors, Find its previous history without a Jof2U to white enrichment redblood cells, No other hematic products of infusion age20-30by the blood between. By testingthe blood donor and the E antigen. Recipients for E antigen negative donor antigen positive forthe group E. Recipients and donor E antigen for negative with the control group, Every50cases.ELISA method to determine the application before a blood transfusion in serum and3,5,10,18days after blood transfusion IgM antibodies, Application flow cytometry determination wasbefore a blood transfusion recipients and after blood transfusion3,5,10,18days CD4+, CD8+positive change law of cells, ELISA method to determine the application before a bloodtransfusion recipients and,3,5,10,18days after blood transfusion lymphocyte IL-2expression.Conclusion E antigen negative patients undergoing E antigen positive blood，The body toproduce antibody, the IgM lymphocyte IL-2, CD4+, CD8+positive cells，All have a rising，Getting a process.