Comparison Of The Risk Factors For Anterior Circulation And Posterior Circulation Ischemic Stroke:a Retrospective Case Series Study

Objective:To investigate the differences of the vascular risk factors for anterior circulation and posterior circulation ischemic stroke.Methods:The unified diagnosis and treatment questionnaires of ischemic stroke in Qingdao city were developed. The data of943consecutive patients with acute ischemic stroke treated in the Departments of Neurology in11hospitals with imaging facilities such as computerized tomography(CT) or magnetic resonance imaging(MRI) in Qingdao city and its surrounding counties from June2008to February2009were collected. The risk factors for anterior circulation and posterior circulation ischemic stroke were analyzed.Result:Univariate analysis showed that there were significant differences in age、sex、 history of coronary heart disease, hyperlipidemia, atrial fibrillation and baseline National Institutes of Health Stroke Scale(NIHSS)score between anterior circulation posterior circulation ischemic stroke (all P<0.05). Multivariate logistic regression analysis showed that the age(odds ratio [OR]1.025,95%confidence interval[CI]1.009-1.042) and the baseline NIHSS score (OR1.052,95%CI1.019-1.086) tend to the anterior circulation ischemic stroke, whereas coronary heart disease(OR0.512,95%CI0.341-0.768)and hyperlipidemia(OR0.585,95%CI0.386-0.884) tend to posterior circulation ischemic stroke, and hyperlipidemia was independent risk factors for posterior circulation ischemic stroke.Conclusions:Vascular risk factors exerted different effects on anterior circulation and. posterior circulation ischemic stroke.