The Frist Part Extrauterine Growth Restiction In Premature Infants With Different Feeding Ways

Objective To explore the incidence of extrauterine growth restriction in premature infants with different feeding ways.Methods 90 cases of premature infants were divided into three groups according to feeding ways:the preterm formula milk feeding group,the human milk feeding group and the mixed feeding group. There were no statistical significance in sex,gestational age, birth weight, head circumference, body length, z score of weight for age(WAZ), among those three groups at birth.Growth indicators such as body weight, head circumference, body length,body weight gain,head circumference gain, body length gain, z score of weight for body length (WHZ) and WAZ were monitored from those infants when they were at the corrected gestational age of 40 weeks,1 month and 2 months.Results The human milk feeding group was higher than the other two groups in body weight,body length,head circumference,body weight gain, head circumference gain, WAZ,and there were statistical significance among three groups when they were at the corrected gestational age of 40 weeks(F=5.110～27.738, P<0.05). The body length gain of the preterm formula milk feeding group was less than the other two groups, and there was statistical significance (F=25.311, P<0.05). At the corrected gestational age of 40 weeks, the EUGR of the human milk feeding was lower than the other two groups, and there was statistical significance (x2=5.366,5.467,P<0.05). At the corrected gestational age of 1 month, the body weight gain and head circumference gain of the human milk feeding group were less than the other two groups, and there were statistical significance (F=8.770,19.482, P<0.05). The body length gain of the preterm formula milk feeding group was higher than the other two groups, and there was statistical significance (F=6.518, P<0.05). At the corrected age of 2 months, the preterm formula milk feeding group was higher than the other two groups in body weight,body weight gain, body length and head circumference gain,and there was statistical significance (F=4.047-17.044, P<0.05). The body length gain of the human milk feeding group was less than the other two groups, and there was statistical significance (F=22.241, P< 0.05)Conclusion Without milk fortifier, at the corrected gestational age of 40 weeks,growth indicators of the human milk feeding group, such as body weight,body length,head circumference,body weight gain, head circumference gain,and WAZ,were better than the other two groups. At the corrected gestational age of 40 weeks, the EUGR of the human milk feeding was lower than the other two groups.At the corrected gestational age of 1 month and 2 months, without milk fortifier, some indicators of of the human milk feeding group,such as,the body weight gain,head circumference gain and body length gain, were less than the other two groups. The preterm formula milk feeding group had the dominant growth in some extent. Objective To explore extrauterine growth restriction(EUGR)of premature infants with mechanic ventilation.Methods 153 cases of preterm infants, according to whether application mechanical ventilation, were divided into mechanical ventilation groups and non-mechanical ventilation group (the common group). There was no statistical significance between two grous in sex, gestational age, birth weight, length, head circumference and z score of weight for age (WAZ) at birth. Indicators,such as, body weight, head circumference, body length,body weight gain,head circumference gain, body length gain, z score of weight for body length (WHZ), WAZ and ratio of extrauterine growth restriction,were monitored from the two groups at the corrected gestational age of 40 weeks. And analyzed the risk factors of the extrauterine growth restriction of the mechanical ventilation group.Results At the corrected gestational age of 40 weeks, body weight, head circumference, body weight gain, length gain, head circumference growth gain of the mechanical ventilation group were lower than the common group, there was no statistical significance between two groups (F=38.74-183.36, P<0.05). The occurrence of EUGR from the mechanic ventilation group was higher than the common group, and there was statistical significance between two groups (x2=4.342,P<0.05).Univariate and multivariate regression analysis showed that pneumonia, gestational age and neonatal asphyxia had the relevance with the occurrence of EUGR,and there were statistical significance (P< 0.05,OR=8.190.0.728,3.635)Conclusion At the corrected gestational age of 40 weeks, the body weight, head circumference,body weight gain, body length gain,head circumference gain of the premature infants with mechanical ventilation were lower than the premature infants without mechanical ventilation. The occurrence of EUGR from the mechanic ventilation group was higher than the common group.In the mechanic ventilation group, gestational age, neonatal resuscitation,pneumonia might be the risk factors of extrauterine growth restriction.