| BackgroundCoronary artery disease(CAD)is common disease, which has serious effects on the health of human beings, and their pathological basis is coronary artery atherosclerosis(CAAS),Carotid atherosclerosis(CAS)and coronary atherosclerosis have common pathology and risk factor, there is a certain correlation, Atherosclerosis (AS), most in the large and medium arteries, with the factors of age growth and bad living habits and so on, It causes artery wall thickening and harden, blood loses elasticity and for reducing luminal stenosis, resulting in viscera function lesions. Atherosclerosis, the main artery of the main features of the change is flexibility reduced. Carotid atherosclerosis as a clinical manifestation of a "window", the elasticity in the early detection will help assess the coronary arteries in patients with structural and functional changes. Although the evaluation of coronary atherosclerosis means more varied, but the current non-invasive evaluation of coronary artery atherosclerosis is still in exploring stage. In recent years, velocity vector imaging (VVI) in the evaluation of regional myocardial function not only the speed, strain, strain rate imaging study has been widely valued, but also in the evaluation of carotid artery gradually carried out. VVI technology and traditional techniques and Doppler compared to much advantage. First of all, VVI mode from the angle of the work; secondly, VVI can obtain information on wall motion in any direction; addition, VVI tracings point tracking based on the common carotid artery intima, automatically determines the movement to the heart center, It is not caused by arterial pulse swing effect, it improves the detection repeatability. Purpose1. Evaluating of carotid artery thickness, plaque and the degree of correlation between coronary artery diseases.2. To explore the varying degrees of coronary artery disease without carotid artery plaques fractional parts of the velocity, strain, strain rate variation.3. To explore the long axis of the common carotid artery intima velocity, strain, strain rate and degree of coronary artery disease, to explore the common carotid artery and evaluation of coronary artery disease without invasive methods.Material and method1. Research object: From March to November 2010 ,60 patients confirmed by coronary angiography in patients with coronary artery disease of different degree of stenosis, 34 male, 26 female, aged 41 to 75 years, mean age(61.8±8.3) years. Normal control 20(12 male;8 female. aged 35 to 73 years, mean age(58.2±10.8) years).2. Instruments: Siemens Acuson Sequoia 512 color ultrasonic diagnostic instrument, 15L8w-s high-frequency probe, frequency of 8 ~ 14MHz,(Siemens syngo US Workplace 3.0) software analysis, Siemens company offers.3. Methods: In this study, Siemens Acuson Sequoia 512 color Doppler ultrasonic diagnostic instrument, of 60 confirmed by coronary angiography in patients with coronary artery disease of different degree of stenosis and 20 normal control group underwent carotid artery ultrasonography, the use of VVI analysis software observed in patients with coronary artery disease in varying degrees of common carotid artery wall short-axis plane of the wall peak systolic velocity (Velocity, Vsm), peak systolic strain (Strain, Ssm) and peak systolic strain rate (Strain rate, SRsm), while observing the long axis of the plane of carotid artery wall peak systolic velocity (Vsm), peak systolic strain (Ssm) and peak systolic strain rate (SRsm), The normal group analysis revealed the severity of coronary heart disease in different carotid artery short axis and long axis of the plane wall of the different state of motion, comparing the different degree abnormalities in patients with coronary artery disease elasticity. Statistic analysis: SPSS 13.0 analysis software, data as mean±deciazione standard, measurement data using t-test,was used to compare rates between variables chi-square test, For all analysis,p value less than 0.05 was considered significant.Results1. Coronary heart disease group carotid intima-media thickness significantly higher than normal group (p<0.05), different coronary lesions in the group of common carotid artery plaque is obviously higher than that of normal incidence. 2. Parts of coronary heart disease without plaque with multi-vessel disease of the double-vessel disease of carotid artery wall short axis radial velocity, strain and strain rate were lower than the control group,p<0.05 was statistically significant; single-vessel disease group compared with the control group wall of no statistical significance.3. Multi-vessel disease coronary heart disease and carotid artery double-vessel disease without atherosclerotic plaque largest long-axis systolic radial velocity, strain rate is lower than the normal control group, p<0.05,statistically significant, Single vessel disease group and control group without statistical significance.ConclusionMore severe coronary artery disease, incidence of carotid atherosclerosis can be higher, it reflects the extent of coronary artery disease. Through the carotid artery detected by ultrasound and VVI can be screened at high risk of coronary artery disease and improve prediction of clinical coronary artery disease, but VVI technology requires high quality two-dimensional ultrasound images, and the operation is a great influence on human factors, there is no uniform reference standard, it requires further. |
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