Wushen Oral Liquid Treatment Of Diabetic Coronary Heart Disease Comorbid Arrhythmia Clinical Observation

To Qi Deficiency on TCM, Western medicine diagnosis of arrhythmia asso-ciated with coronary heart disease patients, combined application of five oral propafenone treatment parameters, and the application of propafenone and simple as the control group, two groups of patients for safety And ef-fectiveness evaluation. The efficacy of five oral argument the mechanism for its clinical and lay a solid foundation.Objective:Observe WuShen oral liquid treatment for TCM syndrome differentiations two qi and Yin deficiency syndrome diabetic coronary heart disease patients with comorbid arrhythmia, safety and effectiveness evaluation. And with western medicine anti-arrhythmic drugs (propafenone), and discusses the positive control mechanism for clinical curative effect, promote and lay a solid foundation.Significance:Expand the clinical treatment of cardiac arrhythmias associated with coro-nary heart disease treatment methods and paths, reducing the burden on pa-tients, after improving the clinical efficacy.Methods:1.186 cases of out-patient and hospital patients were randomly divided into2 groups,treatment group 94 cases,92 cases of control group; all patients by TCM are Qi and Yin Deficiency type, consistent with Western arrhythmia and coronary heart disease diagnostic criteria. Two groups in gender, age, card type, underlying disease and so there was no significant difference (P>0.05), comparable; control group with propafenone 150mg, four times a day, orally, the treatment group using the five parameters Oral Liquid 200ml, three times a day, orally, while giving propafenone 100mg, twice daily, oral, surrounded by a course of treatment2. Observe the patient before symptoms,signs,total efficient and significant efficiency, and do statistics processing, compare its curative effect.3. Laboratory observation blood-test, routine urine and kidney function as shit routine, safety index to determine whether they are toxic side effects of five and oral liquid.4. Clinical monitoring of blood glucose before and after treatment, blood lipids, blood viscosity, CPR, HbAlc, serum fructosamine (FTS) of the changes; fasting blood glucose, postprandial 2 hours once a week check, the two data before and after treatment were statistically analyzed5. Statistical methods:SPSS 13.0 statistical packages application with mean differences. Measurement data (x and standard deviation) said, using t-test, counting material by chi-square test, inspection, grade material using Ridit inspection.Results:The two groups in gender, age, disease severity, etc. There was no signifi-cant difference (P>0.05), comparable. Wushen oral treatment in Chinese medicine symptom score improvement, effective rate is 57.95%, total effec-tive rate was 92.04%; total score improvement in symptoms, total effective rate was 88.63%. These two aspects of the statistical analysis (P<0.05), group differences were significant, the treatment group than the control group; the two groups in blood glucose control throughout the trial process are within the specified scope, excluding fluctuations in blood glucose re-search results, making the number of attacks before and after treatment of arrhythmia observed indicators such as comparable. The two groups of pa-tients before and after treatment fasting blood glucose, postprandial 2 h blood glucose, glycated hemoglobin, serum fructosamine and blood lipids in both the improvement in the statistical analysis, no significant differences between the two groups (P>0.05); in arrhythmia therapeutic effect, the treatment group than the control group, the difference was statistically sig-nificant (P<0.05); improvement in the dynamic electrocardiogram, five oral juice group, could reduce the propafenone group arrhythmia episodes, shorter episodes duration difference between two groups was statistically significant (P<0.05), and compared with the control group, the treatment group less impact on the QT interval, the treatment group than the control group; two groups after treatment, drug side effect The control group was higher than the treatment group, treatment group quit rate of 6.38% in the control group quit rate of 15.21%, the statistical analysis, with significant statistical significance (P<0.05).Conclusion:WuShen oral liquid treat to coronary heart disease parameters associated with arrhythmia, the clinical application of safe and effective.