Clinical Observation On Renal Failure No.â…¢ Recipe Delaying CRF

Chronic renal failure (CRF) is a kind of disease which evolves irreversibility and slowly until Kidney loses function completely and dies away. The disease brings about disasters and heavy economic pressures to human.is developing faster and faster. In order to take about hopes and new treatments and delay the development of the disease, the research about traditional Chinese medical science applies to clinical of Chronic renal failure is more and more important. The article consists of clinical observe and inheritance and literature.The first part, " Clinical observation on Renal Failure No.Ⅲrecipe delaying CRF"Objective:To observe the renal failure No.ⅢRecipe clinical efficacy of chronic renal failure.Methods:To select the First Hospital of Wuhan renal outpatient CRFⅠ-Ⅲof 64 patients, they were randomly divided into two groups, the treatment group of 34 patients, the control group of 30 patients, they were given the same basic treatment, Patients of treatment group took the Renal Failure No.Ⅲrecipe, Patients of control group only took the Medicinal Charcoal Capsules (one kind of sorbent). Observe the change of serum creatinine (Scr),clearance of endogenous creatinine(Ccr),Hemoglobin levels and TCM syndromes integration in before and after therapy.Results:1 two groups of patients before treatment generally (include age, gender, kidney function, anemia index) compare, was not statistically significant (P>0.05), comparable.2 Renal function improvement after treatment compared to the situation changes:the treatment group and the control group Scr decreased, Ccr increased; treatment group and control group compared, the differences were statistically significant, indicating that renal failure No.ⅢRecipe, medicinal charcoal tablets can Improve renal function of patients (P<0.01); treatment group and control group between the two groups compared, the differences were statistically significant (P <0.05). Renal Failure No.Ⅲrecipe is better than Medicinal Charcoal Capsules.3 Anemia Indicators improvement after treatment compared to the situation changes:Treatment group, Hb rised than before, the difference was statistically significant (P<0.01); control group, Hb changed unconspicuous than before, treatment group and control group between the two groups compared, the differences were statistically significant (P< 0.01). Renal Failure No.Ⅲrecipe is better than Medicinal Charcoal Capsules.4 Clinical curative effect comparison: treatment group total effectiveness 64.7%and, the comparison group total effectiveness 40%. Both are statistically significant difference (p< 0.05), Renal Failure No.Ⅲrecipe clinically superior treatment of Medicinal Charcoal Capsules alone.5 Comparison of clinical staging effects:treatment group compensatory stage, discompensation stage, exhaustion stage of the total effective rate was 77.8%,61.9%,50.0%, the difference was not statistically significant (P> 0.05); control group compensatory stage, discompensation stage, exhaustion stage of the total effective rate was 50.0%,42.1%, 33.3%, the difference was not statistically significant (P> 0.05).6 Comparative efficacy of TCM type:treatment group, spleen and kidney yang and spleen and kidney qi deficiency type the total effect, accounting for 90.9% and 87.5%; spleen and kidney yang and spleen and kidney qi deficiency type more effective than yin and yang deficiency, with statistical significance (p <0.05).7Course of treatment, three patients coming from treatment group appeared mild diarrhea, four patients coming from treatment group appeared nausea, after medication dose and time of taking medicine adjusted were improved; five patients coming from control group appeared astriction,the astriction eased after they were given honey water or "fanxieye" water.Conclusion: 1 Renal Failure No.Ⅲrecipe can improve patients with kidney function,'anemia index, delay renal failure.2 Renal Failure No.Ⅲrecipe can significantly improve TCM syndromes integration.3 Renal Failure No.Ⅲrecipe are superior than Medicinal Charcoal Capsules alone.The second part is literature review "huoxuehuayu act on the application of chronic renal failure". From the characteristics of hemorheology in chronic renal failure—High blood viscosity, blood flow slows down, red blood cell deformation increased, coagulopathy, etc and the main performance of renal pathology—Glomerulosclerosis, interstitial fibrosis,Proposed in recent years with "shenluoyuzu" point of view, we conclude that the "xueyuzheng" consistently throughout the chronic renal failure. there is a basis that huoxuehuayu acted on the application of chronic renal failure. According to view of the modern pharmacology, summed up the rhubarb, red sage root, angelica, Chuanxiong role in the mechanism of kidney disease and clinical application. Conclusion part of the proposed method in the current clinical application of "huoxuehuayu" during the main problems.