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Changes Of Cardiac Function In Perioperative In Elderly Patients By Ultrasound Cardiac Output Monitor

Posted on:2012-12-27Degree:MasterType:Thesis
Country:ChinaCandidate:J R ZhangFull Text:PDF
GTID:2214330368493171Subject:Anesthesia
Abstract/Summary:PDF Full Text Request
Objective Ultrasound cardiac output monitor(USCOM) to can be used to observe①the influence of the different general anesthetic inductionon cardiac function in elderly patients.②the changes of cardiac function of the elderly hypertensive patients in different risk stratification of perioperative period so as to optimize the effect of clinical treatment.Methods Part one : compared with the influence of the different general anesthetic inductionon cardiac function of elderly patients. Selected 75 cases with non-cardiac surgery of American Anesthesiologist Association(ASA)Ⅰ~Ⅱin aged patients, then divided them into there groups stochasticlly, sevoflurane group (S), propofol group (P) and midazolam group (M),with 25 cases in each.These three groups were monitored the left ventricular cardiac output (CO), stroke volume (SV), systemic vascular resistance (SVR),velocity peak (Vpk), ejection time(ET) percent, heart rate (HR) situation by USCOM in five time points including before the induction of general anesthesia (T0), before intubation 1min (T1), after intubation 2min (T2), after intubation 5min (T3),and after intubation 10min(T4).Part two : studied on the cardic function change of hypertenssive elderly patients from different risk stratification of perioperative period. Elderly hypertensive patients with no cardiac surgery were selected and divided into the following 4 groups: groupsⅠ(low-risk), groupⅡ(dangerous), groupⅢ(high-risk) and control group (without hypertension), each group with 30 cases. These four groups were monitored the left ventricular cardiac output (CO), stroke volume (SV), systemic vascular resistance (SVR),velocity peak (Vpk), ejection time(ET) percent, heart rate (HR) situation by USCOM in seven time points including before the induction of general anesthesia (T0), before intubation (T1), immediately after intubation (T2), the beginning of operation ( T3 ), intraoperative 1 hours ( T4 ), surgery ( T5 ) and extubation ( T6 ) monitoring in patients with left ventricular output ( CO ), each Bo output ( SV ), peripheral vascular resistance ( SVR ), peak velocity ( Vpk ), percentage of net ejection time ( ET ) and heart rate (HR ) condition.Results Part one : compared with the situation in T0 , MAP and SVR of group S and group M were declined obviously (P <0.05);CO,SV,Vpk, MAP and SVR of group P were decreased significantly (P <0.05, P <0.01)and ET was prolonged (P <0.05). Compared with group S and group M, MAP and SVR of group P were declined obviously in T1,T2,T3,T4(P <0.05); compared with group M, SVR of group S was down significantly in T1, T2, T3, T4 (P <0.05).Part two : Compared with T0, CO,SV,Vpk,SVR and HR of control group T1 was significantly lower, and the difference had statistical significance (P < 0.05). Compared with T0, groupⅠ, groupⅡand groupⅢT1,T2,T6 , CO,SV,SVR, Vpk and ET was lower significantly, the difference had statistical significance(P<0.05).Compared between control group, groupⅠ, groupⅡand groupⅢeach other T0,T1,T2,T3,T4,T5,T6; CO,SV, SVR, Vpk and ET are significantly changed , and it had statistical significance(P< 0.05).Conclusion①Three kinds of general anesthetics could be inducted safely and effectivly on American Anesthesiologist Association( ASA)Ⅰ~Ⅱelderly patients, but the inhibition on the cardiac function of elderly patients is the biggest with propofol, and the smallest with midazolam in three groups.②The cardiac function of elderly patients with hypertensive had a significantly changes during perioperative period, the higher the risk level is, the more apparent the cardiac change is , the higher the risk is.
Keywords/Search Tags:Elderly, General Anesthesia induction, Cardiac function, Ultrasound cardiac output monitoring, Hypertension
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