Analysis Of MSCT Signs Of Lung Cancer And Benign Lesion Designed To Identify Of Malignant And Benign Lesion

Objective: Retrospective comparative analysis of MSCT signs of lung cancer and pulmonary benign masses designed to compare similarities and differences, look for the more specific signs of malignant and benign lesion and the accuracy of the diagnosis, find the reason for misdiagnosis and compare the misdiagnosis with the correct diagnosis of lung cancer aims to discuss differential diagnosis between the two to further improve the accuracy of clinical diagnosis of lung cancer.Material and methods: 87 cases with pathologically or clinical imaging data proved were reviewed from January 2007 to July 2009.including 46 cases with correct diagnosis, 22 males, 24 females, age range 40~77 years old, mean age 58.65+ 9.10 years old; 41 cases with misdiagnosis, 18 males, 23 females, age range 35~79 years old, mean age59.24+12.27 years old. . 43 cases were collected over the same period with a benign tumor or lesion, 17 males and 26 females, aged 20~82 years, the average age of 55.12 years. All cases were scanned by 4 or 16 multi-slice spiral CT with 2.0~5.0mm collimation. Observed lesion size, distribution and lesion edge and internal signs of the diagnosis and differential diagnosis in the conventional lung window and the mediastinal window and imaging findings showed a comprehensive analysis of causes of misdiagnosis. By SPSS16.0 for statistical analysis, t test measurement data applications, Chi-square test applied to count data and ordinal data P <0.05 as significantly different standards .Results: Misdiagnosis and the correct diagnosis of lung cancer cases in the availability of lobulation, spiculation and pleural indentation sign on the X~2 value and the P values were X~2 = 8.335 P = 0.004; X~2 = 15.501 P = 0.000; X~2 = 8.785 P = 0.003, P values were <0.05; vessels convergence in both and bronchial gas cluster signs on the P values were> 0.05. Lung cancer cases will show lobulation, spiculation, vessels convergence, bronchogram and pleural indentation. These signs are divided into three levels, 0 ~1 is not typical, 2~ 3 is more typical, 4 ~5 is typical. Correct diagnosis and misdiagnosis group level difference on X~2 = 12.548, P = 0.002. Overall analysis, patient factors, doctor's subjective judgments and inexperienced mistakes are the objective technical reasons for misdiagnosis of pulmonary benign and malignant nodules.Conclusion: The CT signs of benign and malignant pulmonary nodules or masses have certain characteristics and overlaps, the typical cases were diagnosed more easily, overlapping or atypical cases cause misdiagnosis, reasons of misdiagnosis of atypical cases are lack of technical inspection, also diagnosis are not allowed for medical certification, lack of experience and other subjective factors. CT showing pulmonary nodules or masses having lobulation, spiculation, vascular convergence, bronchogram and pleural indentation, is conducive to the diagnosis of lung cancer. An effective method to reduce the misdiagnosis of pulmonary nodules is comprehensive analysis of various CT signs combined with clinical experiences.