Analysis Of Risk Factors For Esophageal Cancer

Objective:To explore the general epidemiological characteristics and the main risk factors for esophageal cancer (esophageal squamous cell cancer and adenocarcinoma) of 171 cases from the affiliated hospitals of Jilin University to provide a theoretical basis for the prevention and control strategies for esophageal cancer.Methods:171 cases of patients who were definitely diagnosed as esophageal cancer by endoscopic biopsy and postoperative pathology in the first affiliated hospital of Jilin University during 2004.01~2011.03 with relatively complete case information were selected as experimental group. And 216 cases without tumor diseases of digestive tract from medical examination center of the same hospital were selected as control group. There were no significant differences in ethnicity, age and gender between the two groups and all the cases were residents in Changchun city for more than 10 years.Results:A logistic regression analysis was performed and indicated that the odds ratio (OR) of secondhand smoking, alcoholic beverage consumption, higher temperature diet, eating too fast, drink and eat too much at one time (surfeit), fried food, salty pickled vegetable, roast and smudging food was 4.265, 5.755, 9.091, 7.637, 5.241, 3.218, 5.502, 2.847, respectively, while the OR of bean products , fresh fruits and vegetables as well as onion and scallion was 0.143, 0.096, respectively.Conclusion:Secondhand smoking, alcoholic beverage consumption, higher temperature diet, eating too fast (meal time under 10 minutes),drink and eat too much at one meal (surfeit), fried food and salty pickled vegetable were risk factors for esophageal cancer, in contrast, bean products, fresh fruits and vegetables as well as onion and scallion were proved to play a protective role to some certain in the progress of esophageal cancer. The research helped in screening out the risk factors and protective factors of esophageal cancer through logistic regression analysis, which provided a theory basis for the prevention and control strategies for esophageal cancer .