Passes The Tongbitang Addition And Subtraction Treatment Class Rheumatic Arthritis The Curative Effect Observation

Goal:The observation Tongbitang addition and subtraction to treat cold wet category rheumatism arthritis the clinical curative effect.Uses Tongbitang addition and subtraction to treat cold wet categoryrheumatism arthritis, through observes its clinical curative effect, the objective evaluation Tongbitang addition and subtraction to treat cold wet category rheumatism arthritis the clinical curative effect. And discusses its effective mechanism, for further promotes the Chinese medicine union to treat cold wet category rheumatism arthritis to build the foundation.Method:1. Clinical materialsWere all from October 2009 to October 2010 Orthopedic Hospital of Hubei Province during the inpatient or outpatient orthopedic patients, in line with the diagnostic criteria for rheumatoid arthritis. All patients met the diagnostic criteria selected 72 cases wind cold rheumatoid arthritis patients as research subjects, 17 patients were male, female,55 were randomly divided into two groups, the treatment group of 36 patients in the control group of 36 patients two groups of patients by gender, age duration of illness, etc. No statistically significant difference (P< 0.05), comparable.2. Outcome measuresBefore and after treatment the main symptoms and signs [including joint pain level of visual acuity test table method (VAS), joint tenderness, joint swelling number (the number of joint tenderness, swelling the number of calculations:Bilateral proximal interphalangeal, metacarpophalangeal, wrist, elbow, shoulder, knee, total 28 joints), duration of morning stiffness (min), average grip strength of both hands (mmHg), joint functional class, symptom scores and so on.] [2] and make a record.Statistical Methods:The measurement data with±s, the significance of the measurement data compared with the t test,2 groups significant test the efficacy of using Ridit analysis3. TreatmentTongbi Decoction treatment group based side, prescription consists of:living alone Notopterygium 10g 10g 10g wind Loranthaceae Guizhi 12 g angelica lOg 15g lOg Poria Rehmannia Eucommia 20g 12g 15g sea breeze rattan Arctiin Frankincense 15g 30g 6g Drynaria Myrrh 10g according to TCM syndrome with the addition and subtraction cards. Wind Piansheng were added wind, Notopterygium, Clematis, were added when cold Piansheng Radix, Kusnezoffii Guizhi, Asarum, Wet Piansheng by adding barley, Dioscorea collettii. Shuijianbi, first with warm water for 30min, a large open, slow fire boiling gently for 30min,2 times against the fried juice 300ml, minutes morning and evening, warm clothes, day 1. Control group with oral administration of nimesulide (force the United States Song) dispersible tablets, each 100mg,2 times a day, plus methotrexate tablets, every 7.5mg,1 time per week.2 groups were 8 weeks a course of treatment, once every 4 weeksObservation4 Clinical standards for efficacy4.1 According to the literature, "Practical Chinese Rheumatology" [3] formulation. Clinical cure:the symptoms disappeared, normal functional activities; the main indicators of normal physical and chemical examination. Markedly:The main symptoms of all to remove or eliminate the symptoms, joint function was restored, can participate in normal work and labor; indicators of physical and chemical examination were normal. Effective:The main symptoms basically eliminated, the main joint function recovered or have significant progress, life can not take care of themselves become able to take care of themselves, or loss of employment and the ability to work into labor and the ability to work has been restored; key indicators have improved physical and chemical examination. Invalid:and before treatment compared to no improvement in all aspects4.2 Clinical indicators:the level of joint pain, including visual acuity test table method (VAS), joint tenderness, joint swelling number (the number of joint tenderness, swelling the number of calculations:bilateral proximal interphalangeal, metacarpophalangeal, wrist, elbow, shoulder, knee, total 28 joints), duration of morning stiffness (min), average grip strength of both hands (mmHg), joint functional class, symptom scores and so on. Joint function, joint function classification level on the reference to ACR criteria [2]; syndrome score in the standard reference "Chinese medicine treatment of rheumatoid arthritis drugs Guidelines for clinical research" [2] developed by none, mild, moderate and severe different Split as 0,2,4,6 points.4.3 adverse events observed:adverse drug reactions, nimesulide (force the United States pine) tablet and side effects of methotrexate tablets mainly as stomach upset, nausea, vomiting, stomach pain, rash, itching, dizziness, headache. [4]Results:1. Clinical effects:the efficiency of the treatment group and the total effective rate was better than the control group.2. Adverse reactions:the control group and 12 cases of adverse reactions, accounting for 33.33%; while the treatment group,2 cases of adverse reactions, accounting for 5.56%, the treatment group than in the control group, a lower incidence of adverse reactions (P<0.01).Conclusion:This topic comparison comparison way, take passes rheumatism soup addition and subtraction side as the observation group, the Nepali America Shurly armor ammonia pterin piece is a control group, after observes the treatment separately the clinical symptom improvement situation, through statistics processing, draws the conclusion:The Chinese native medicine passes rheumatism soup to add and subtract can effective treat cold wet category rheumatism arthritis, its effectiveness is higher than the control group, also the clinical use security, responds not good lowly, for further promoted the Chinese medicine treatment class rheumatism arthritis to provide certain scientific basis.