| Triamcinolone Acetonide Acetate and Econazole Nitrate Cream for fungal infections associated with a tendency to fungal infection or dermatitis, eczema; by the dermatophytes, yeasts and mold fungi caused by inflammatory skin diseases such as foot and ringworm, tinea, jock itch, tinea versicolor; diapers sex Dermatitis; candidiasis angular cheilitis; paronychia; by fungi, bacteria of the skin caused by mixed infection. Dosage is:topical, applied to the lesion,1 day sooner or later. Occasionally a small number of patients with localized allergic reactions such as skin burning, itching, tingling and so on. Long-term heavy use may be similar to the cortex when hyperthyroidism, such as hirsutism, acne, wounds are not healing.Triamcinolone Acetonide Acetate and Econazole Nitrate Cream with econazole nitrate and triamcinolone acetonide two components. Are imidazole derivatives econazole, is broad-spectrum antifungal agents with anti-dermatophytes, yeasts, fungi, Pityrosporum role. It has griseofulvin, nystatin, penicillin antibacterial spectrum of cable three drugs. Considerable efficacy and neomycin. The triamcinolone acetonide is a glucocorticoid steroid hormone, has significantanti-inflammatory, anti-exudative, anti-proliferative, anti-allergic, anti-itching effect. Compatibility between the treatment of superficial fungal disease, not because of triamcinolone acetonide effects of immune suppression and anti-fungal activity of econazole, on the contrary, the two collaborative, anti-inflammatory at the same time itching to kill fungi, rapidly relieve symptoms, and concomitant eczema and dermatitis are the best. This product can inhibit the fungus, but also reduce the fungal infection caused by inflammation and allergic reactions, there is extensive clinical application, especially for those with obvious superficial fungal infection of inflammatory cases, with rapid onset, only itch obvious symptoms than single preparations for the excellent and good and patient compliance. Popular formulations of the drug were also welcome, do not pollute the clothes, not greasy, and non-irritating. Related to pharmacology and toxicology, clinical trial data showed that Triamcinolone Acetonide Acetate and Econazole Nitrate Cream in the production and use are safe, effective and quality controlled.The experiment Triamcinolone Acetonide Acetate and Econazole Nitrate Cream for pharmaceutical research, research mainly includes three parts:triamcinolone econazole cream formulation technology research, triamcinolone econazole cream in the quality of the research, Triamcinolone econazole cream preliminary stability.First, the research component in the formulation process, our primary consideration to moderate viscosity, good stability, bright color, uniform thickness and other factors studied. The results show that the prescription process through research and technology through our prescription products, prepared to reach out the Chinese Pharmacopoeia 2005 cream formulation of the relevant requirements.Secondly, the quality of parts, we have established a preparation of character, identification, PH value, determination, microbial limit, percutaneous absorption, and other aspects of the relevant material. By chromatography, spectroscopy, chemical analysis and other methods. Through the study found that the products comply with the 2005 version Pharmacopoeia standards.Finally, the subject of the prepared triamcinolone econazole cream preliminary stability studies, the impact factor test, acceleration test and long-term stability of the experimental study to examine the stability of preparations, the experimental results show that the drugs according to the Ministry of Health the provisions of the standard will be valid for a period of 24 months, tentatively; storage conditions and stability test results and information according to national standards set as follows:sealed in a cool place saved. |
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