| OBJECTSTo explore the effect of dietary nutrition and related factors on women with malignant tumor (ovarian cancer) disease, providing basis for nutritional recommendations to prevent and control the women tumor.METHODSAdopting case-control study method, selecting female patients who have been treated in department of gynecology in hospital affiliated to Inner Mongolia Medical College, during march 2007 to january 2009, as the research objects(aging 20-65 years). The 47 patients in case group haven't been done surgery, radiotherapy and medication before come to the hospital, but all were diagnosed as ovarian cancer patients by histopathology diagnosis after the surgery (mean age51.43±8.46 8.46 years).At the same time, according to age and regions matching, selecting 64 patients from the same hospital but were not ovarian cancer patients as control group (average age 48.86±7.92 years), then observing the records of all objects and doing questionnaires.Investigation contents including basic information (age, occupation, education, body mass index, family income, family history of tumor, marital status); women related information (menarche age, marriage age, childbearing age, contraceptive methods, bearing children count, lactation way, gynecological check-up frequency); dietary nutrition information (eating habits, all kinds of food intake frequency). Using spssl3.0 to deal data by t-test,X2 inspection, single factor and multi-factor Logistic regression analysis.RESULTS1.For basic information, compared with case group, proportion of high education, month income in the control group is higher; proportion of BMI> 25.0, family have tumor history, unsuccessful marriage or misfortunes is lower; the age, occupation has no obvious difference between the control group and the case group. Results of t-test show that BMI, family income, family history of tumor, marital status has significant difference between two groups (P<0.05 or P<0.01).2. For information related to women, the proportion of women in the control group married aging 20 to 25 years old, childbearing age<30, taking the breastfeeding mode, doing gynecological check-up are more than the case group. The marriage age, childbearing age in case group is higher than those in the control group, and the scale that artificially feed the baby also higher than that of the control group. Indicators of menarche age, contraceptive methods, fertility children count has no obvious difference between the two groups. Statistical analysis results show that, index of the marriage age,childbearing age, lactation way, frequency of gynecological check-up has significant difference between the two groups (P<0.05 or P<0.01).3. For dietary information, the proportion of drinking liquor, drinking tea, intaking of bean products, vegetable, fruit and the bland diet in the control group is obviously higher than the case group. Eating sweets, high fat food, salted food, piddle or junk food and the intake ratio of meat, eggs, milk, and cereal are obviously lower than the case group. Statistical analysis showed that the intake frequency of corn, soybean, milk have no significant difference between the two groups (P>0.05). The intake frequency of drinking wine, drinking tea, sweets, vegetables and fruits, high fat food, eggs, meat and preserved food have obvious difference between the two groups (P<0.05). Analyzing those factors gradually by conditions logistic multiple regression analysis, the results showed that BMI, family history of tumor, eat fatty foods are risk factors for women with ovarian cancer, OR are 3.545,258.342,186.286 respectively,which means that high BMI, having a family history of tumor, eating high fat food can promote the occurrence of female ovarian cancer. Eating vegetables every day is the protection factor for ovarian cancer, the OR is 0.106, which means that eating more vegetables every day can prevent the ovarian cancer.CONCLUSION1. BMI>25.0, family income is low and having a family history of tumor, failed marriages or misfortune have certain effect on the occurrence of ovarian cancer2. Marriage age>25 years, childbearing age>30, artificial feeding the baby, don't always do gynecological check-up that have certain effect on the occurrence of ovarian cancer.3. Small doses of liquor, often drinking tea, often eating bean products, eating more vegetables and fruits, eating less sweet food, meat, high fat food and preserved food can prevent the occurrence of ovarian cancer.4. The significant factor for the occurrence of women ovarian cancer is high BMI, often eating high fat food; eat more vegetables is the protection factor for ovarian cancer.5. The ovarian cancer is the result of many factors. |
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