Dynamic Observation In Minimally Invasive Treatment Of Cerebral Hemorrhage

Objective:Explore the clinical value of minimally invasive surgery by detecting S100B, BMP and NSE inimally invasive surgery for intracranial hematoma in patients with hypertensive cerebral hemorrhage.Methods:78 patients with hypertensive cerebral hemorrhage were randomly divided into surgical group (41 patients) and conservative group (37 patients), another 40 health were taken as normal control group. Serum S100B, BMP and NSE level were dynamic detected by enzyme-linked immunosorbent assay in 1th (before surgery),3rd,7th,14th day.Results:â‘ MBP levels of patients with cerebral hemorrhage on day 1 at the onset was significantly higher than the control group,4,7d reached a peak, the incidence began to decline 7 to 9, but still higher than the control value, duration of 28 days, returned to normal, brain Bleeding within 24 hours after onset,7 days,14 days neurological deficit scores were positively correlated with the MBP. Operation group,14,28 days after surgery serum MBP was significantly lower than medical therapy group. Operation group after treatment compared medical treatment group differences in neurological function 14d,28d statistically significant.â‘¡NSE levels of patients with cerebral hemorrhage on day 1 at the onset was significantly higher than the control group, reached a peak on day 3, the first 14 days was still significantly higher than the control group.1 day,3 days,7 days,14 days neurological deficit scores and the NSE content showed significant positive correlation. NSE peak and parenchymal hematoma volume were positively correlated. Operation group,7,14,28 days after surgery was significantly lower than serum NSE medical therapy group. Operation group after treatment compared medical treatment group differences in neurological function 14d,28d statistically significant.â‘¢S100B protein in patients with cerebral hemorrhage that is higher, significantly higher than in the 3d peak, then gradually declined to 14 d when the still higher.1 day,3 days,7 days,14 days neurological deficit score and S100B protein content showed significant positive correlation. Operation group 3,7,14 day after surgery serum S100B protein were significantly lower than medical therapy group. Operation group after treatment compared medical treatment group differences in neurological function 14d,28d statistically significant.â‘£All detection targets were positively correlated with the amount of bleeding with no obvious correlation between the bleeding site. The targets were observed with neurologic deficit scores can have a relationshipConclusion:All observed indicators were significantly increased, and a positive correlation with the amount of bleeding, indicating that these three indicators can reflect the brain tissue of stroke damage.Serum levels were above indicators in patients with cerebral hemorrhage and prognosis of the disease correlated significantly, as acute intracerebral hemorrhage is simple, cheap and effective predictor of blood.Minimally invasive treatment of cerebral hemorrhage hematoma can significantly reduce the hemorrhage MBP, NSE, S100B protein level, significantly reduce the extent of brain damage cerebral hemorrhage and cerebral hemorrhage significantly reduced neurologic impairment.