| Chronic rhinosinusitis (CRS) refers to the chronic inflammation of nasal cavity and the paranasal sinus mucous membrane,which continues for more than 12 weeks and is getting more and more serous.It is a common disease in the clinical.when chronic rhinosinusitis had failed in the standard case of medical treatment, surgical therapy has become an important treatment. With the continuous development of medicine,functional endoscopic sinus surgery (FESS) has become the preferred surgical treatment.The fundamental cure for this disease is the loss of mucosal inflammation,.Mucosal recovery is a hot research after surgrey. Nasal cilia function is normal or not, which has a closely relationship with the nasal inflammation。This research will study Biyuan Heji on the impact of postoperative nasal cilia movement, to further quantify in traditional Chinese medicine use in rhinosinusitis patients,Objection:This topic is designed to observe the Biyuan Heji on the ciliary movement of Chronic rhinosinusitis after the impact of FESS. And discuss the using of Chinese medicine in the value of FESS Postoperative, to provide objective data and provide clinical practice for the participation of Chinese medicine after the FESS surgery.Method:This clinical study was divided into three stages, in the first stages of research programs, according to the latest clinical research literature to made diagnosis standard, observation target,mark standard, appraisal standard of efficacy and so on.According to the recent teaching material of statisties to fix the numbers of Patients.In the second stage of clinical studies, the patient will be randomly divided into two groups, controlling group and the observation group; two groups of patient were measured MTT before surgery, to Calculate MTR and subjective symptom scores.Both groups were treated with the same Preoperative care and postoperative nasal endoscopy regularly care, The observation group patient will take Biyuan Heji after the surgery,In the same time, both groups were measured MTT before nasal endoscopy examination, and record the subjective symptoms and clinical adverse reactions. The third stage will collection and collation data in statistical analysis.Conclusion:the MTR and the subjective symptoms have no significant difference before FESS.(P>0.05),The MTR and the subjective symptoms alao have no differents after the fourth the week of the FESS.(P>0.05),But after the eigth week of FESS, the MTR of the both groups have differernts, and only the Headache and Runny nose score show differents (P<0.05),.The MTR which has differences between the group in the twelfth week(P<0.01), when the two groups were compared, subjective symptom scores in the twelfth weeks of purulent nasal discharge flow in patients with symptoms of both groups compared (P<0.05), statistically there is no difference in other symptoms. The Patients in both groups compared to the total MTR(P <0.01),show significant difference. The Total score of subjective symptoms show differernt (P <0.05).We can know the MTR Of observed group in the second week compared with the preoperative show difference Statistically(P<0.05), while the MTR of control group begin to have some differernt (P<0.05). in the third week.Conclusion:Nasal mucosa cilia system have gradually restored after the FESS, and Biyuan Heji can improved the nasal ciliary transport function and the subjective symptoms, in the same time,to speed up the recovery of nasal cilia.We can get the test for the postoperative Biyuan Heji provides more objective datafor the Chinese medincine in the future. |
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