Clinical Outcomes Of Pereutaneous Coronary Intervention For Left Main Coronary Artery Stenosis

Objective:To observe the efficacy of percutaneous coronary interventional for patients with unprotected left main coronary artery disease evaluated by EUROscore and SYNTAXscore, and the relation between EUROscore, SYNTAXscore and clinical factor.Methods:The clinical data of 75 patients with unprotected left main coronary artery disease who were treated in the Department of Cardiology, Tianjin Chest Hospital from Jan.2008 to Dec.2010 were collected. The data included general conditions (gender, age, coronary heart disease, etc), risk factors (smoker, hypertension, diabetes mellitus. hypercholesterolemia, etc), biochemical index (serum creatinine, serum uric acid, cholesterol, LDL-c, etc), cardiac function (end-diastolic left ventricular diameter and left ventricular ejection fraction), angiographic characteristics of coronary (CAG). PCI treatment (stent type, method of operation, etc) and postoperative medications, etc.Results:1,In the present work, patients were strictly selected. Average age was 61 years and the mean LVEF was 60% (only two patients with an LVEF of=40). success rate of immediate surgery was 100%. No MACE occurred during hospitalization. Long-term follow-up results show that the MACE-free survival rate was 92.7% The results suggested that stenting in patients with unprotected left main coronary artery disease was a safe and effective treatment.2,ByΧ2 test, PEARSON correlation analysis, show that the integral and EURO score,SYNTAXscore correlation (r=0.368, P<0.05), that there is consistency in the application of the two. Negatively correlated with LVEF SYNTAXscore; SYNTAX score correlation integral and LVEDD.3,By EURO integration group and the variance analysis of the clinical parameters visible EURO integration and is clearly related to smoking.4,Patients with LMCA in the elderly group, gender differences and no significant correlation SYNTAX score, suggesting that older men and women in the degree of coronary artery stenosis no significant difference, EUROscore the male than female, suggesting that female patients with left main disease risk PCI procedure than men.5,SYNTAXscore and TC, LDL-C non-correlated; EUROscore and TC, LDL-C non-correlated.Conclusion:1,EUROscore, SYNTAXscore scoring in the low risk zoning of unprotected left main coronary artery PCI treatment has a good safety and efficacy, can be used as safe and effective treatments of unprotected left main coronary artery disease.2,SYNTAXscore, EUROscore can be common as a basis for risk assessment of left main coronary artery interventional therapy, have practical value. LVEF as reflecting the severity of coronary stenosis index.3,EUROscore and smoking are obviously related, prompts smoking is an important factor affecting EUROscore assessment PCI risk.4,Gender differences are not SYNTAXscore evaluation of PCI in patients with left main coronary disease risk risk factor.5,TC, LDL-C not SYNTAXscore. EUROscore evaluation LM PCI for patients with risk factors of risk.