| Objective:To study the employment CysC and serum correlation between coronary heart disease. Methods:select definitely suspected because of chest pain, doing coronary heart disease patients with coronary angiography check the clinical data of 76 cases, according to the coronary angiography results into CHD group (AMI group, UA group, SA group) and the normal group, each group according to gender, age, smoking history, high blood pressure, diabetes, hyperlipidemia, Glu, Cr, BUN, CsyC comparison; According to coronary angiography results and will CHD group is divided into 1 a lesion group,2 teams of three cigarettes lesions with lesions group. Use of latex particle enhance immune determination of serum GSH than turbidity employment CysC concentrations, an illness, and pathological damage from coronary heart disease, coronary lesions Gensini integral counts and employment STT research serum with coronary heart disease in the relationship between the C. Results:1 with employment CysC leels of serum glutathione leels, coronary heart disease, coronary lesions illness progressive Gensini integral increase; count and When in acute myocardial infarction because acute phase to reflect the serum employment CysC level drops glutathione; 2 Logistic regression showed that: employment STT C and serum GSH without significantly associated with coronary artery disease (OR= 5.324,95%CI2.235-12.812P＜0.01); 3 multiple stepwise regression displayed in the correction factors such as age, gender, serum GSH after employment Cys C and Gensini coronary lesions total score still independent existence. Conclusion: employment CysC leels of serum GSH with coronary heart disease occurrence, development is closely associated with coronary heart disease can be indirectly reflect an illness, and pathological damage, lesions count and lesions range. |
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