Henoch-schonlein Purpura Animal Model And Flavored Lithospermum Soup Arthus Reaction The Role Of Experimental Research

Purpose:Animal model of allergic purpura production and Modified Lithospermum Tom purpura on an animal model of allergic mechanismMaterial and method:Methods Rabbitâ…¢type hypersensitivity, the overall conditions in the perspective of the cellular immune Modified Lithospermum anaphylactoid purpura Treatment Study.Results:1. Modified lithospermum decoction can reduce the Rabbitâ…¢-type hypersensitivity skin reaction intensity, and the model group decreased swelling diameter (P <0.05) were significantly different.2. Modified lithospermum decoction can reduce the IL-2 serum levels on Rabbitâ…¢-type hypersensitivity model (P> 0.05), there is a tendency, no significant difference.3. Modified lithospermum decoction can reduce the CIC serum levels on Rabbitâ…¢-type hypersensitivity model (P> 0.05), there is a tendency, no significant difference.Conclusion:The results show that,â…¢-type hypersensitivity can be used as an animal model of allergic purpura, flavored soup Lithospermum type hypersensitivity skin irritation onâ…¢inhibitedâ…¢type hypersensitivity in rabbits on circulating immune complexes (CIC) and the IL -2 levels inhibit the trend. Modified Radix decoction can lead to serum levels of circulating immune complexes decreased, while typeâ…¢allergy restraining, this may be the treatment of allergic purpura mechanisms.