Autologous Bone Marrow Blood Stem Cell Transplantation Combined With Traditional Chinese Medicine Treatment Of Diabetic Foot Clinical Research

Purpose:Application the methods of autologous bone marrow stem cell transplantation to treatment of diabetic foot, observation and assessment the clinical efficacy of combination of Chinese mdiceine and autologous bone marrow and blood stem cell transplantationMethod:60 cases with severe lower limb ischemia in diabetic foot patients which meet the inclusion criteria were divided into the conventional therapy group (A group) 20 cases, a total of 38 limbs, autologous bone marrow blood stem cell transplantation for the treatment group (B group n=20), a total of 39 limbs, autologous bone marrow blood stem cell transplantation in combination with Tongmai Huayu Decoction treatment group (C group) 20 cases, a total of 38 limbs. After 12 weeks of treatment, efficacy observation of indicators such as limb pain, cold flu, rest pain, claudication distance, ankle-brachial index, while follow-up and observe whether the associated complications and adverse reactions.Results:1. A group of indicators before and after treatment of the observed difference was not statistically significant (P<0.05).2.12 weeks after transplantation, B group and C group transplantation group, limb limb pain, cold flu, rest pain, claudication distance compared with transplantation (P<0.05); transplantation group, the mean ankle-brachial index after transplantation was significantly higher than before the transplantation (P<0.05), since the mean difference between transplantation group were significantly higher (P<0.05). Transplantation group, ulcer healing rate was significant.3. Transplantation group, the rate of lower limb amputation was significantly lower than the control group. Grafting and surgical complications and adverse reactions. Conclusion:This study established autologous bone marrow blood stem cell transplantation therapy which can ease the symptoms of diabetic lower limb ischemia, increase collateral circulation and improve lower limb blood supply, while promoting the healing of foot ulcers, and it is a simple, safe and effective treatment of diabetic foot.