Red Blood Cell Suspension To The Scattering Properties Of The Mueller Matrix Characterization And Experimental Research

Blood is an important kind of human tissue, the blood test method is often used in clinical diagnosis. However, not only the existing blood test method is inconvenient for real-time, but also increases the probability of infection. Therefore, the achievement of non-invasive diagnoses technology for blood is of great value in clinical diagnosis. Based on the background, the polarization property of the backscattered light of the RBC suspension is discussed, and the conclusions could be summarized as follows:Theoretically, the backscattered 2D Mueller matrix of RBC suspension is simulated with the VMC method based on the Mie theory and the equivalent particle model. The polar decomposition algorithm is used to extract information from the raw Mueller matrix and the depolarization index, the diattenuation index and the retardance index of the RBC suspension are calculated.Experimentally, the backscattered 2D Mueller matrix of RBC suspension is measured by the oblique incident and perpendicular detecting experimental facility, the experiment results matches well with the simulation ones. Furthermore, RBC suspensions under different ratio is measured and a series of meaningful conclusions are drawn:In the isotonic solution, with the increasing of RBC concentration, the scattering probability is increased and the depolarization index and the diattenuation index are reduced which means the depolarization ability of the media is enhanced; In the hypertonic solution, the depolarization ability of the suspension also improves with the increasing of the shrinkage level of the RBC; In the hypotonic solution, the depolarization index monotone increases with the increasing of hemolysis level, but the variation of diattenuation index of the hypotonic RBC solution is not monotonous, this result indicates that the depolarization index describes the hemolysis level well and the reason of the non-monotonic variation of diattenuation index needs to be further studied.Both of the theoretical and the experimental results provide new information for the implementation of non-invasive diagnoses technology for blood.