| Objective:To explore the clinical efficacy and drug mechanism of GanKangliShuiFang on Alcohol hepatocirrhosis ascites through influencing on ALT,AST,γ-GGT,child grade,abdominal circumference and the condition ascites fadeaway .Methods: Fifty patients were divided into two groups randomly. The 25 patients in the treated group were treated by KKLSF combinate Antisterone and Furosemide and the 25 patients in the control group were only treated by Antisterone and Furosemide . Ascites subsided situation,Change of liver function,Ascites subsided, the urine volume increased and the abdominal circumference, ascites volume changes were measured before and after treatment.Results: The total effective rate in the treated group was significantly higher than that in the control group(P<0.05). Serumlevels of ALT,AST/ALT significantly improved (P<0.05) ,and 24-hour urine volume increased significantly than that before treatment(P < 0.05) , Abdominal circumference decreased significantly than that before treatment(P<0.05),Ascites decreased depth(P<0.05)。Conclusion: GKLSF has a role in Ascites subsided .the mechanism may be relative to protecting cells of liver,promotion of liver cells on amino acid uptake and regeneration,promote the absorption of sodium and water metabolism,inhibition of protein decomposition,elevated levels of plasma albumin. Ascites can be subsided though the mechanism. |