Objective:This research inherits the traditional Chinese medicine theory of following the prognosis of a disease,clinically,proceeding from DOS infrequent menstruation patients 40 years ago,and investigates the method of invigorating the kidney and regulating the chong,ren meridian to improve the symptom and to effect the ovarine reserve function.The study expect to provide an effective new way for preventing premature ovarian failure.Methods:30 women with DOS infrequent menstruation patients of affiliated hospital-based outpatient obstetrical clinic are chosen as case resources.The therapeutic method is invigorating the kidney and regulating the chong,ren meridian,and the prescription is decocted in water for oral dose,trimenon for a course of treatment.Symptoms are observed pre-and post-treatment,and score them; Electrochemistry radiation method has been used to examine follicle-stimulating hormone(FSH),luteinising hormone(LH)and estradiol(E2) pre and post treatment.Results:(1) Preceding treatment,the symptoms of delayed menorrhea or hypomenorrhea,waist and knee sour and weak,insomnia and dreaminess,flush and sweating,restlessness or testiness are obvious. After cantly better than before(P<0.05).The overall efficiency of regualting menstruation is 83.33%.(2) The integral of symptoms is decreased significantly compared with pre-treatment in groups(P<0.05, P<0.01).The patients in the therapeutic group post-treatment,2 cases fully recover from an illness,excellence is 7 cases,effectiveness is 17 cases,unavailability is 4 cases,total effective rate is 86.67%,also a patient of infertilitas feminis pregnant.(3) Patients serum bFSH,bLH after treatment is obviouisly lower than that of pretherapy(P<0.01),as to bE2 level go up,bLH level descend,but is of no significant difference(P>0.05).The method of invigorating the kidney and regulating the chong,ren meridian can possiblely regulate bFSH level to treat the DOS.Conclusion:It is very important to evaluate the ovarine reserve function earlier and to treat the DOS in time for preventing amenorrhea, infertility,POF and so on.The main pathogenesis is renal deficiency, damage of essence,insufficiency of blood and chong ren.The method of invigorating the kidney and regulating the chong,ren meridian can improve the general symptom and make a part of patients regular menstruation,also lower the bFSH level.It is possible to become a good method for treating the DOS clinically. |