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Physical Health Acupoint Paste The Pharmacy Part Of The Study

Posted on:2008-07-04Degree:MasterType:Thesis
Country:ChinaCandidate:T YangFull Text:PDF
GTID:2204360272464300Subject:Pharmacy
Abstract/Summary:PDF Full Text Request
Qiang shen bao jian xue wei tie is Radix Astragali and Radix Angelicae Sinensis ingredient made by the Chinese Babuji, according to Chinese medicine theory Meridian Point, play drug percutaneous absorption Meridian Point and the effect of therapeutic effect and role in human Point "Shenque Point" mainly used to strengthen the body's immune system. The subject in the theories of traditional Chinese medicine, under the guidance of modern science and technology for the preparation of pharmaceutical research.Based on the ingredient chemical composition analysis, combined with modern pharmacology research, orthogonal design. with a comprehensive evaluation to select the optimal extraction process; Also identified purification, the enrichment process; Selection of PVA, gelatin, HR, glycerol as the matrix to bond strength, toughness, evenness of the indexes integrated score, The optimum use of matrix ratio, the best screening Process.Franz diffusion cell use method of in vitro percutaneous absorption and release in vitro experiments, HPLC skin acceptable solution acceptable solution and the release of index components-ferulic acid by HPLC method. In vitro release test, the release followed the Higuchi Equation release curve dynamics model. Meanwhile the pilot-plant test and quality standards, identify Radix Astragali and Radix Angelicae Sinensis on the TLC; to establish a separate HPLC Astragaloside and ferulic acid determination, the establishment of the corresponding content limits of HPLC and the quality control standards on the basis of this preliminary preparations for stability. The study results show Preparation reasonably practicable, quality control standards, product quality.
Keywords/Search Tags:Qiang shen bao jian xue wei tie, Preparation, Quality standard, Percutaneous absorption, Stability
PDF Full Text Request
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