Integrative Medicine Compared The Efficacy Of Non-surgical And Surgical Treatment Of Peptic Ulcer Perforation

Objective: To compare clinical effect of non-surgical therapy of traditional Chinese medicine integrated with western medicine with that of surgical therapy in treating patients suffered from peptic ulcerous perforation. Methods: From October 2005 to October 2007, the clinical data of 95 patients with peptic ulcerous perforation was analyzed retrospectively. Result: of the 41 patients treated by non-surgical therapy, 40 were healed successfully, with 1 case transferred to operation. No complications happened in all of the 41patients. Peptic ulcer disappeared in 93.2% of the 41patients one year later and no relapse happened during follow-up. Of the 54 cases treated by operation, 53 were cured, 1 suffered from incision infection postoperatively, 1 suffered from intestinal obstruction., and 1 died. Peptic ulcer disappeared in 94.3% of the 54 patients during follow-up for one year. There was no significant difference between two groups in the rate of peptic ulcer disappearance and complication, however, the expenditure and the date in hospital was lower in non-surgical group (p<0.05). Conclusion: Non-surgical therapy has the similar therapeutic effect in treating peptic ulcerous perforation, compared with that of surgical therapy. Non-surgical therapy possesses advantages such as safety, effectiveness, convenience and low expenditure, and can be accepted by patients more easily.