Clinical Research, In Chongzhikeli Granule Treatment Of Vascular Dementia (, Spleen And Kidney Deficiency And Phlegm Awakened Card)

Purpose: Observer Congzhi Keli treatment of Vascular Dementia (insufficience of kedney and spleen with the turbid and gore toxin type) clinical efficacy.Method: In clinical study, 60 patients with Vascular Dementia are randomized into treatment group(Cong Zhi Keli, 30 case)and control group(Co-dergocrine Mesylate Tablets, 30 case), adopting the stochastic parallel double blind double simulation comparison observation. Treatment group received Cong Zhi Keli per oral. 1 bag, three times daily together with simulation tablets of Co-dergocrine Mesylate Tablets per oral. 1 tablet, three times daily for 12 weeks,while the control group received Co-dergocrine Mesylate Tablets each time 1 tablet, three times daily and simulation keli of Cong Zhi Keli per oral. 1 bag, three times daily for 12 weeks.Results: the curative effect in cognition function,conduct capability,memory,computation ability and directing power between the treatment group and the control group were similer (P>0.05). It explained the Cong Zhi Keli may enhance patient's intelligence . In the improvement disease symptoms aspect, the treatment group surpasses the control group . (P<0.05 or P<0.01)Conclusion: Cong Zhi Keli can obviously improve Vascular Dementia (insufficience of kedney and spleen with the turbid and gore toxin type) patient's clinical symptoms . This clinical study showed Cong Zhi Keli has good curative effect and does not have obvious the poisonous side effect and adverse reaction.