Methods of restrospective study were adopted in the study. 99 COPD patients in the stable phase were observed. The course of disease, pulmonary function, arterial blood gas analysis, D-dimer, fibrinogen(Fbg) and the relativity between these indexes above-mentioned and the different traditional Chinese medicine(TCM) Syndrome type were analyzed. The objective regularity of TCM pathogenesis in COPD and the relationship between it and those modern medicine indexes were approached. It was to provide objective basis for the TCM Syndrome type of COPD stable phase relatively. The results indicated that the course of disease increased gradually(P<0.05)from Fei Deficiency, Fei-pi Deficiency, Fei-shen Deficiency to Fei-pi-shen Deficiency; and the rate of obstructive emphysema, chronic cor pulmonale increased(P<0.05); the level of D-dimer, Fbg(the indexes of blood stasis) ascended(P<0.05);the level of pulmonary ventilation function declined, the level of RV/TLC ascended gradually(P<0.05); the level of PaO2 declined, the level of PaCO2 ascended, but the difference of Fei-shen Deficiency and Fei-pi-shen Deficiency was not evident(P<0.05),others were all evident.Conclusions: the study disclosed that the course from Fei Deficiency, Fei-pi Deficiency, Fei-shen Deficiency to Fei-pi-shen Deficiency was a progress of disease from light to serious by the observation of indexes in COPD stable phase. And the outcome provided objective basis for TCM Syndrome type of COPD stable phase relatively. |