Caga~+ Relationship Between Hypertensive Gastropathy And Helicobacter Pylori Infection Research On Relationship Between TCM Syndrome Types

Objective: It is to study the relationship between TCM syndrome-type of chronic gastritis and peptic ulcer and infection of Helicobacter Pylori (H. pylori) with CagA gene. Methods: The syndromes of seventy patients diagnosed chronic gastritis and peptic ulcer by serum diagnostic were analyzed. According to the differentiation of syndromes, these patients were divided into five TCM syndrome-types: dampness-heat in both spleen and stomach type , disharmony between liver and stomach type , dampness-heat in deficient spleen type , spleen deficiency with obstruction of Qi type, and deficiency-cold of both spleen and stomach type. The relationship of age, gender, period of diseases, state of illness, classification of H. pylori and five TCM syndrome-types was observed at the same time. Results: (1) The proportion of the dampness-heat in both spleen and stomach type (25. 3%) and dampness-heat in deficient spleen type (38. 7%) are more than 50% altogether. There was significant relation between deficiency-cold of both spleen and stomach type and duodenal ulcer (DU) (P<0. 01), and between dampness-heat in deficient spleen type and chronic atrophic gastritis (CAG) (P<0. 01) as well. (2)In CAG there was significant relationship between gender and state of illness and five TCM syndrome-types (P<0. 05). Conclusion: The TCM syndrome-type of chronic gastritis and peptic ulcer infected by H. pylori with CagA gene are mostly caused by dampness heat factor. Among these diseases, there are significant difference between the TCM syndrome-type of DU and CAG. In CAG there is some relationship between gender as well as the degree of pathological change of gastric mucosa and TCM syndrome-type.