As a classic prescription for melancholiac symptoms of stasis from Qi, blood, anger, digestion, fever and phlegm, Yueju Pill that had been made by Zhu Danxi hundreds years ago, was used to cure tympanites and impetuosity caused by liver-Qi depression, which was like melancholia. This article employed the approach of modern pharmacology, to observe Yueju Pill' s antidepressant effect on the animal' s model of acquired, pharmic and chronically irritable melancholia, to analyze its pharmacological functions of antidepressant effect, and to research the changes in animals' neuro-transmitter based on the model of animals' liver depression .It' s proved that the ancient Yueju Pill had good antidepressant effects on several models of animals' melancholia, and it could reduce nervous tension, improve hemorheology index of the animals of liver depression greatly, increase their neuro-transmitter, and ameliorate their living quality. |