The Capsule Portion Of The Nose And Sport Immune Anti-inflammatory Effect And Mechanism

BiKang capsule has the effects of dredging opening and relieving pain, clearing away heat-evil and eliminating toxic materials,promoting blood circulation and removing gore. Using BiKang capsule to treat acute rhinitis,chronic rhinitis and allergic rhinitis and so on has preferable effects.Through clinical to verify, this prescription have better curative effects for many years. In order to study its anti-inflammatory and immune function and its mechanism further ,this subject has carried on following experiments to study: By means of the measuring engulfing function of mice's RES cell and weight of mice immune organ, the producing of the amount of haemolysis plain antibody in the mice body, delayed type hypersensitivity of mice induced by DNCB and verify bikang capsule's impact on mice immune function. By means of the copying the rats model of rhinitis, measuring the activities of of spleen's NK cell and the transformation ratio of spleen's lymphocyte, while measuring the content of the prostaglandin and histamine and malonyl dialdehyde in the mice's inflammatory tissue and probe into BiKang capsule's anti-inflammatory and immune mechanism partly. Results: BiKang capsule can significantly enhance engulfing function of mice's RES cell and weight of mice immune organ, the producing of amount of haemolysis plain antibody in the mice body . BiKang capsule can inhibit late hairdo allergic response of mice skin induced by DNCB at the same time.BiKang capsule can strengthen NK cell's activities and lymphocyte's transformation ratio of the rats model of rhinitis too and depress the content of the prostaglandin and histamine and malonyl dialdehyde in the in the mice'sinflammatory tissue tissue. effects:BiKang capsule can improve normal immune function obviously ,can suppress mice delayed type hypersensitivity obviously ,can resist type IV allergy. Its anti-inflammatory and immune mechanism relates to strengthenning NK cell's activities and lymphocyte's transformation ratio and reducing of the content of the prostaglandin and histamine and malonyl dialdehyde too.Above-mentioned results indicate that bikang capsule is while treating various kinds of rhinitis, not merely confine to anti-inflammatory and analgesic effects., may also strengthen the curative effects through improving the immune function and the resistance against diseases of the organism .