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Kdz Stasis Of Blood Rheology And Vascular Endothelin

Posted on:2002-08-04Degree:MasterType:Thesis
Country:ChinaCandidate:R WeiFull Text:PDF
GTID:2204360032450576Subject:Chinese medical science
Abstract/Summary:PDF Full Text Request
Purpose: Kudiezi inject The text probes the imPact principle of ion (made of the abstractsof Ixeris sonchghlia Hance) to the common blood stasis syndrome of heart and brainangiopathy by observing the relevance index of hemorrheology' the endothelin of illpersons and the pattern of b1ood stasis syndrome of animal experimentation Methods:62ill persons of blood stasis syndrome of heart and brain angiopathy are divided into 3groups in non-choice method: 32 persons for Kudiezi injection; 30 persons fOrFufangdanshen injection; 30 persons fOr normal comParison group. The c1inical curativeeffects and the index of whole blood viscosity' plasma viscosity. re1ative viscosity.erythrocyte accumulate index and the level of endothelin of il1 persons are observed and 二comPared respect1vely before treatment and after 14 days tf eatment.In addition, 50 Wistarrats are divided into groups:40 rats made of blood stasis pattern;10 rats for normalcomParison group.The animals are injected separately Kudiezi injection (20 rats) andFufangdanshen injection (l0 rats)in the abdondnal cavity with high and low doses,theabove index are observed again.Result:The in person of blood stasis syndrome of heartand brain angiopathy. The ratio between the mass effect of the treatment for Kudieziinjection and that of Fufangdanshen injection is proximity, Fufangdanshen injection has theobvious effect of activating the blood circulation to eliminate blood stasis. This affrms theeffect of activating the blood circulation to eliminate blood stasis of Kudiezi injection andenlarges the clinical aPply zone of Kudiezi injection.dex of hemorrheology and theendothin of blood stasis syndrome persons are notable high. The ratio between the indexof blood stasis syndrome person and that of normal person is notable difference (p<0.01).The ratio between the index of hemorrheology and the endothelin with Kudiezi injectionand Fufangdanshen injection before treatment and that of after treatment is low (p<0.05 orp<0.01). The mass effect of the treatment for Kudiezi injection is 84.4%, The mass effectof the the treatment for Fufangdanshen injection is 80.0%, the datum of two group isproximity (P>0.05). In animal experimentation, The ratio between the index ofhemorrheology and the endothelin for the pattern of blood stasis syndrome of animalexperimentation and that of normal group is high (p<0.05 or p<0.0l). The ratio betweenthe index of Kudiezi injection (high and low doses grouP). the index of Fufangdansheninjection and that of animal experimentation pattern group is low (p<0.05 or p<0.0l). Theratio between the index of hemorrheology and the endothelin of Kudiezi injection (highand low doses group) and that of Fufangdanshen injection is proxlmity(p>0.05).Conclusion:The high datum of hemorrheology and the endothin for persons ofblood stasis syndrome and the animal experimentation pattern rats lead to the blood stasissyndrome.Kudiezi injection brings down the index of hemorrheology and the endothelin ofthe person of blood stasis syndrome of heart and brain angiopathy .The ratio between themass effect of the treatment fOr Kudiezi injection and that of Fufangdanshen injection isproximity. This affirms the effect of activating the blood circulation to eliminate bloodstasis of kudiezi injection and enlarges the clinical apply zone of Kudiezi injection.
Keywords/Search Tags:Kudiezi injection, heart and brain angiopathy, blood stasis syndrome, hemorrheology, endothelin
PDF Full Text Request
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