Theoretical And Clinical Research On Spleen-tonifying, Dampness-resolving, Stasis And Toxin-removing In The Treatment Of Advanced Colorectal Carcinoma

Object:To observe the clinic effect of Jian Pi Hua Shi Qu Yu Jie Du decoction in the treatment of advanced colorectal tumor.Method:30 cases of advanced colorectal tumor were chosen and randomly divided into two groups,15 cases of trail group were treated with Jian Pi Hua Shi Qu Yu Jie Du decoction and chemotherapy with FOLFOX scheme another 15 cases of control group were treated with chemotherapy with the same scheme only.Compare the two groups in clinical symptom amelioration,the level of serum CEA,degree of side effects caused by chemotherapy and physical strength,and count out the difference in the upper aspects between the two groups.Result:The effective rate of Chinese medicine syndrome evaluation in trail group is 86.67%,the rate of control group is 60.00%.Two groups have Statistically significant differences(p<0.05).It states that the trail group has more prominent advantage than the control group in terms of Relieving clinical symptoms. The KPS before the treatment of two groups'patients have no statistically significant differences. However, the KPS after the treatment of two groups'patients have statistically significant differences(p<0.05).It shows that the trail group has more advantages than the control group in aspect of improving general conditions of patients. CEA has the particular evaluation in diagnosing colorectal cancer.CEA before the treatment of two groups'patients have no statistically significant differences. However, CEA after the treatment of two groups'patients has statistically significant differences. It demonstrate that the trail group also has more advantages than the control group in aspect of reducing CEA value. Recent objective efficiency of curing tumor in the trail group is 33.33%.It is a bit higher than the control group (20.00%).Two groups have no statistically significant differences (p>0.05).Conclusion:In the treatment of advanced colorectal tumor, Jian Pi Hua Shi Qu Yu Jie Du decoction proved it's function in enhancing the effect of chemotherapy, relieving the toxic and side effects caused by chemotherapy, improving the immune function, ameliorating living quantity and prolonging the life span.